疑似先天梅毒患儿的梅毒血清学预后及影响因素分析  

influencing factors analysis of the follow-up results of suspected congenital syphilis in NanShan

作　　者：袁军 田丽闪 谭艳 杨祖庆 吴秋红 罗珍胄 

机构地区：[1]广东省深圳市南山区慢性病防治院皮肤性病科,518054

出　　处：《检验医学与临床》2016年第A02期58-59,共2页Laboratory Medicine and Clinic

摘　　要：目的评估疑似先天梅毒患儿的预后及其影响因素，以及预防性治疗的干预效果。方法归纳分析十年来我区476例疑似先天梅毒患儿的治疗及梅毒血清学结果随访，对结果进行统计学分析。结果19S-IgM的检测对于确诊先天梅毒有较高的敏感性（94．4％）及特异性（100％）。19S-IgM阴性的疑似先天梅毒患儿，血清学滴度低于母亲血清学滴度4倍者预后良好，可不用预防性治疗。结论19S-IgM在早期先天梅毒的诊断中具有重要意义，疑似先天梅毒患儿需要加强随访和复查，仅有相应异常的患儿中可应用预防性治疗。Objective To analyze the follow-up results and influencing factors of suspected congenital syphilis in NanShan from 2006 to December 2015. Methods Retrospective analysis for 476 suspected congenital syphilis infants and referred to Nanshan. Resuits 19S-IgM antibody detection shown certain sensitivities（94.4%） and specificities（100%）. The follow-up results of infants with 19S-IgM antibody negative and serological titer four times less than mathers are good,It is suggsted that preventive treatment is nonessential. Conclusions：19S-IgM antibody detection may usesd to diagnosis. Conclusion syphilis. It is suggsted that suspected congenital syphilis should be increase the frequency and duration of follow-up. Preventive treatment only used on corresponding abnormal infants.

关 键 词：先天梅毒 预后 预防性治疗 

分 类 号：R714.259[医药卫生—妇产科学]