双模式联合镇痛方案在膝骨性关节炎患者人工膝关节置换术后快速康复中的应用效果  

Application efficacy of dual-mode analgesic scheme in enhanced recovery after total knee arthroplasty in patients with knee osteoarthritis

作　　者：谭景超[1,2] 邓宝贵[1] 潘海文[2] 张柱基 刑庆嘉 杨俊兴[1] 

机构地区：[1]广州中医药大学第一附属医院四骨科,广州市510000 [2]广州中医药大学研究生院,广州市510000

出　　处：《广西医学》2017年第1期75-77,共3页Guangxi Medical Journal

摘　　要：目的探讨双模式联合镇痛方案在膝骨性关节炎患者人工膝关节置换术后快速康复中的应用效果。方法选择行单侧人工膝关节置换(TKA)的膝骨性关节炎(KOA)患者65例,随机分为对照组31例与试验组34例。两组均于术后当天、术后第2及3天使用帕瑞昔布钠静脉注射1次,试验组在此基础上术前1 d外用丁丙诺啡透皮贴。比较两组患者术后第2天和第4天的疼痛视觉模拟评分(VAS)、住院时间及术后曲马多使用总剂量。结果试验组患者术后第2天、第4天VAS、住院天数、术后曲马多使用总量均低于对照组患者(P<0.05)。结论对于行TKA的KOA患者给予双模式联合镇痛方案可达到良好的镇痛效果,缩短住院周期,减轻患者康复过程中的疼痛感。Objective To investigate the efficacy of dual-mode analgesic scheme in enhanced recovery after total knee arthroplasty （TKA） in patients with knee osteoarthritis （KOA）. Methods Sixty-five patients with KOA undergoing unilateral TKA were selected, and randomly divided into control group（ n = 31 ） or experimental group（ n = 34）. Both groups were administrated with parecoxib sodium intravenously fight after surgery,2 days and 3 days after surgery. The experimental group was externally given buprenorphine transdermal patches 1 day before surgery. Visual Analogue Scale（VAS） 2 days and 4 days after surgery,hospital stay ,and the postoperative usage dose of tramadol were compared between the two groups, Results VAS of 2 days and 4 days after surgery,hospital stay,and postoperative usage dose of tramadol in the experimental group were less than those in the control group（all P 〈0.05）. Conclusion For patients with KOA undergoing TKA,dual-mode analgesic scheme can obtain a good analgesic effect,shorten the hospitalization period,and relieve patients＇ pain in the rehabilitation process.

关 键 词：膝骨性关节炎 人工膝关节置换 双模式联合镇痛 丁丙诺啡透皮贴剂 帕瑞昔布钠 快速康复 

分 类 号：R687[医药卫生—骨科学]