嘌呤信号与针灸镇痛  

Purinergic Signaling and Acupuncture Analgesia

作　　者：黄露梅 刘娟[1] 尹海燕[1] 余曙光[1] Patrizia Rubini Peter Illes 唐勇[1] 

机构地区：[1]成都中医药大学针灸推拿学院,四川成都610075 [2]莱比锡大学医学院,德国莱比锡04107

出　　处：《成都中医药大学学报》2016年第4期1-4,131,共5页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：973计划(2015CB554504);中德科学中心(GZ919);四川省青年科技创新研究团队(2014TD0018;2015TD0010);四川省属高校科研创新团队(16TD0015);国家自然科学基金(81373735);国家留学基金委(ICPIT)项目

摘　　要：疼痛是针灸的优势适应症。解析针灸镇痛的机制是一个具有理论和现实意义的重要挑战。继Geoffrey Burnstock提出嘌呤信号参与针灸镇痛的假说以及Maiken Nedergaard证实穴位局部腺苷受体介导针刺镇痛之后,嘌呤信号成为近年来针灸镇痛的研究热点。因此,本文将对嘌呤信号与针灸镇痛的系列研究进行总结以及展望。Increasing evidence has shown the effectiveness of acupuncture in relieving pain. Understanding the mechanisms of acupuncture-induced analgesia is a challenge of great theoretical and practical significance. The hypothesis of Geoffrey Burnstock and the astounding findings of Maiken Nedergaard on the involvement of purinergic signaling in the beneficial effects of acupuncture fertilized the field and led to an intensification of research on acupurines. In this review, we will summarize the state-of-the-art situation and try to forecast how the field is likely to develop in the future.

关 键 词：嘌呤信号 针灸镇痛 

分 类 号：R245.81[医药卫生—针灸推拿学]