麝香风湿跌打膏质量标准研究  

Study on quality control of shexiang fengshidieda plaster

作　　者：王静[1] 吴贵华[1] 王杰[1] 

机构地区：[1]天津市药品检验所,天津300070

出　　处：《天津药学》2016年第6期18-21,共4页Tianjin Pharmacy

摘　　要：目的：建立麝香风湿跌打膏的质量标准。方法：采用薄层色谱法鉴别麝香风湿跌打膏中的川芎;采用气相色谱法测定制剂中龙脑和薄荷脑的含量。结果：薄层色谱法鉴别色谱特征斑点清晰;气相色谱法测得龙脑在0.099 06~0.990 62 mg/ml范围内线性关系良好（r=0.999 9,n=6）,平均回收率为101.9%,RSD为1.9%;薄荷脑在0.141 04~1.410 40 mg/ml范围内线性关系良好（r=0.999 9,n=6）,平均回收率为103.2%,RSD为1.3%。结论：该方法快速简便,准确可靠,专属性强,重复性好,可用于麝香风湿跌打膏的质量控制。Objective：To establish the quality standard for Shexiang Fengshidieda Plaster. Methods：The rhizome of chuanxiong in Shexiang Fengshidieda Plaster was identified by a TLC method. The contents of borneol and menthol were determined by GC.Results：The developed TLC spots were quite clear. Borneol showed a good linear relationship within a range of 0. 099 06 ~0. 990 62 mg/ml. The regression equation was Y = 1. 018 5 X-0. 006 8（r = 0. 999 9,n = 6）. The average recovery was 101. 9%and RSD was 1. 9%. Menthol showed a good linear relationship within a range of 0. 141 04 ~ 1. 410 40 mg/ml. The regression equation was Y = 1. 061 7 X-0. 017 3,（r = 0. 999 9,n = 6）. The average recovery was 103. 2% and RSD 1. 3%. Conclusions：This method is accurate,sensitive,specific and easily handled. It can be applied to quality control of Shexiang Fengshidieda Plaster.

关 键 词：麝香风湿跌打膏 质量标准 龙脑 薄荷脑 

分 类 号：R927.1[医药卫生—药学]