支原体肺部感染患儿的临床实验室影像特征研究  

Clinical laboratory imaging features of children with Mycoplasma pulmonary infections

作　　者：马莲美[1] 王建强[2] 付洪杰[1] 张鑫雨[1] 张倩[3] 

机构地区：[1]滨州医学院附属医院儿童呼吸与重症科,山东滨州256600 [2]滨州市人民医院普外一科,山东滨州256610 [3]菏泽市立医院儿科,山东菏泽274031

出　　处：《中华医院感染学杂志》2017年第2期432-435,共4页Chinese Journal of Nosocomiology

基　　金：山东省医药卫生科技发展计划项目(2013WS0312)

摘　　要：目的探讨支原体肺部感染患儿的临床实验室影像特征,为临床及时诊治支原体肺部感染提供有效参考。方法选取2011年5月-2016年5月医院住院治疗的肺炎患儿479例,根据实验室的检测结果将患儿分为支原体肺部感染组(MPP)98例和非支原体肺部感染组(NON-MPP)381例,比较两组患儿的临床表现、实验室指标、影像学特征以及治疗后转归情况。结果 MPP组患儿的病程、发热时间均高于NON-MPP组,MPP组患儿的咳嗽评分高于NON-MPP组,且差异有统计学意义(P<0.05);MPP组伴随湿啰音患儿比例低于NON-MPP组患儿,MPP组尿检异常患儿比例高于NON-MPP组患儿,差异有统计学意义(P<0.05);两组患儿WBC、NET、CRP、ALT含量差异无统计学意义;MPP组患儿大片肺浸润比例、胸腔积液比例、肺不张比例、结节影比例、支气管血管束增粗比例以及淋巴结肿大的比例显著高于NON-MPP组,差异有统计学意义(P<0.05);MPP组患儿的住院时间、退热时间、咳嗽缓解时间、湿啰音消失时间均高于NON-MPP组,且差异有统计学意义(P<0.05),治疗2周后,MPP组患儿WBC含量、NET含量的差异无统计学意义,MPP组患儿出院后咳嗽超过1个月的比例显著高于NON-MPP组,且差异有统计学意义(P<0.05)。结论支原体感染患儿病程长、咳嗽症状明显且恢复周期长,影像学可以有助于及时判定支原体感染,为临床及时的诊治支原体肺部感染提供了一个有效途径,值得临床推广。OBJECTIVE To explore the clinical laboratory imaging features of children with Mycoplasma pulmonary infections so as to provide guidance for effective clinical diagnosis and treatment of M. pulmonary infections. METHODS A total of 479 children with pneumonia who were hospitalized from May 2011 to May 2016 were enrolled in the study and divided into the Mycoplasrna pulmonary infection group （MPP） with 98 cases and the non- Mycoplasrna pulmonary infection group （NON-MPP） with 381 cases according to the clinical laboratory examination result. The clinical manifestations, laboratory indexes, imaging features, and treatment outcomes were observed and compared between the two groups of children. RESULTS The course of disease and fever time were longer in the MPP group than in the NON-MPP group, and the cough score of the MPP group were higher than that of the NON-MPP group（P〈0.05）. The proportion of the children with wet rales was lower in the MPP group than in the NON-MPP group, and the proportion of the children with abnormal urine test was higher in the MPP group than in the NON-MPP group（P〈0.05）. There was no significant difference in the level of WBC, NET, CRP, or ALT between the two groups of children. The proportions of the children with large pulmonary infiltrates, pleural effusion, atelectasis, nodules, hronchiolectasis, and lymphadenectasis were significantly higher in the MPP group than in the NON-MPP group（P〈0.05）. The hospitalization duration, fever relieving time, cough remission time, and wet rales disappearance time were longer in the MPP group than in the NON-MPP group（P〈0.05）. There was no significant difference in the WBC or NET content of the children in the MPP group after the treatment for 2 weeks; the proportion of the children who had cough for more than one month after they were discharged was significantly higher in the MPP group than in the NON-MPP group（P〈0.05）. CONCLUSION The children with Mycoplasma infection are characterized by long disease course, o

关 键 词：支原体 肺部感染 儿童 影像特征 

分 类 号：R725.6[医药卫生—儿科]