明胶海绵联合替硝唑预防下颌阻生智齿拔除术后干槽症疗效观察  

Clinical Efficacy of Tinidazole Gelatin Sponge in Preventing Dry Socket after Extraction of Mandibular Impacted Teeth

作　　者：李罗玉 李伟力[1] 王新丽[1] 

机构地区：[1]北京市昌平区医院口腔科,北京102200

出　　处：《中国药业》2017年第1期46-48,共3页China Pharmaceuticals

摘　　要：目的观察明胶海绵联合替硝唑预防下颌阻生智齿拔除手术后患者的干槽症的临床疗效。方法将医院2014年2月至2016年2月收治的行下颌阻生智齿拔除术患者128例,按照随机数字表法分为明胶海绵治疗组(A组)和单纯替硝唑治疗组(B组),各64例。其中A组患者在下颌阻生智齿拔除术后采用明胶海绵联合替硝唑预防干槽症,B组患者则在下颌阻生智齿拔除术后单纯使用替硝唑预防干槽症。比较两组患者的干槽症及不良反应发生情况。结果 A组干槽症发生率为0,B组干槽症发生率为7.81%,差异有统计学意义(P<0.05);A组不良反应发生率为7.81%,B组为9.38%,差异无统计学意义(P>0.05)。结论明胶海绵联合替硝唑预防患者,可有效降低下颌阻生智齿拔除术后干槽症的发生率,促进患者的恢复,减轻患者痛苦,具有临床应用价值。Objective To observe and analyze the gelatin sponge combined with tinidazole in prevention of dry socket of the clinical effect of patients with impacted mandibular third molar surgery. Methods 128 cases of patients receiving treatment for impacted mandibular third molar surgery in the hospital from February 2014 to February 2016 were selected and divided into the gelatin sponge treatment group（group A） and simple tinidazole treatment group according to the random number table method, 64 cases in each group. Group A was treated with gelatin sponge combined with tinidazole to prevent dry socket after operation of mandibular impacted wisdom tooth extraction, whiXe group B was treated with tinidazole for prevention of dry socket after operation of mandibular impacted wisdom tooth extraction. The incidences of dry socket and the incidence of adverse reactions were compared between the two groups. Results The incidence rate of dry socket in group A was O, which was much lower than 7.81% in group B（ P 〈 0. 05）. The incidence rate of adverse reactions in group A was 7.81%, which had no statistically significant difference with 9.38% in group B （P 〉 0.05）. Conclusion The preventive effect of gelatin sponge combined with tinidazole on mandibular impacted wisdom tooth extraction can effectively reduce the incidence of dry socket syndrome after the operation, promote the recovery of the patient and relieve the pain of the patient, which certainly has clinical application value.

关 键 词：明胶海绵 替硝唑 干槽症 下颌阻生智齿拔除术 

分 类 号：R969.4[医药卫生—药理学] R988.2[医药卫生—药学]