中国2000年后急性心肌梗死患者抑郁患病率的Meta分析  

The incidence of post-myocardial infarction depression among acute myocardial infarction patients in China during the 2000s: a meta-analysis

作　　者：艾聪[1,2] 李光校[1,2] 周波[1,2] 张鹏[1,2] 何俏[1,2] 时景璞[1,2] 

机构地区：[1]中国医科大学附属第一医院临床流行病学与循证医学教研室,沈阳110001 [2]辽宁省循证医学中心,沈阳110001

出　　处：《中国循证医学杂志》2017年第1期47-51,共5页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统研究中国大陆地区急性心肌梗死(AMI)后患者抑郁的患病率,为AMI患者的临床护理工作提供指导。方法计算机检索Pub Med、The Cochrane Library(2016年6期)、CNKI、CBM、万方数据库及维普数据库,搜集关于中国AMI后患者抑郁患病率的横断面研究,检索时限从2000年1月至2016年6月。由2位评价员独立筛选文献、提取资料并评价纳入研究的方法学质量后,釆用CMA 2.0软件进行Meta分析。结果共纳入22个横断面研究,AMI病例数为2 986例,发生AMI后抑郁的患者1 239例。Meta分析结果显示,中国大陆地区AMI后患者抑郁的总患病率为42.7%[95%CI(36.3%,49.4%)];其中不同的性别、地区、抑郁量表类型和发表年份的AMI后患者抑郁的患病率差异无统计学意义(P>0.05)。结论中国地区的AMI患者患病后抑郁的患病率较高,并且患病率大致呈逐年上升趋势,对于这一现状应引起更多的关注。Objective To estimate the incidence of post-myocardial infarction depression among Chinese acute myocardial infarction （AMI） patients by meta-analysis and to provide references for the management of AMI patients. Methods We searched databases including PubMed, The Cochrane Library （Issue 6, 2016）, CNKI, CBM, WanFang Data and VIP from January 2000 to July 2016, to collect literature regarding the incidence of post-myocardial infarction depression among patients with AMI. Two reviewers independently screened literature, extracted data and evaluated the methodological quality of the included studies. Then meta-analysis was performed by using Comprehensive Meta Analysis （CMA） 2.0 software. Results Totally, 22 cross-sectional studies were included, involving 2 986 AMI patients, of which 1 239 were post-myocardial infarction depression patients. The overall incidence of post-myocardial infarction depression among the AMI patients was 42.7% （95%CI 36.3% to 49.4%）. There was no statistical differences observed when the studies were stratified by sex, regions, scales and years （all P values〉0.05）. Conclusion In China, the incidence of postmyocardial infarction depression is high and rising year by year roughly among AMI patients. The status should be paid more attention.

关 键 词：急性心肌梗死 抑郁 患病率 META分析 

分 类 号：R542.22[医药卫生—心血管疾病] R749.4[医药卫生—内科学] R-03[医药卫生—临床医学]