大气细颗粒物对实验动物氧化应激及炎症反应研究进展  

Research progress in atmospheric fine particles(PM_(2.5)) induced oxidative stress and inflammatory reaction in experimental animals

作　　者：史云洁 王沛[1] 马姗婕[1] 王鑫[1] 何梅[1] 

机构地区：[1]北京市营养源研究所,100069

出　　处：《中国公共卫生》2017年第1期35-38,共4页Chinese Journal of Public Health

基　　金："十二五"农村领域国家科技计划课题(2012BAD33B01-3);北京市自然科学基金(L150008);北京市科学技术研究院联合资助项目北京市科学技术研究院科技创新工程项目(PXM2015_178102_000001);北京市科学技术研究院创新团队计划课题(IG201407C2)

摘　　要：流行病学研究显示,大气细颗粒物(PM_(2.5))可引发人体呼吸系统、心脑血管系统等方面的疾病。为了更详细地了解PM_(2.5)对人群健康的危害,本文针对PM_(2.5)在动物实验中氧化应激和炎症反应方面的影响进行了归纳总结,为进一步研究PM_(2.5)对机体的危害提供理论依据。Epidemiology studies find that fine particles （ particulate matter less than 2. 5 μm in aerodynamic diameter, PM2.5 ） is associated with increased incidence and mortality of respiratory, cardiovascular and cerebrovascular diseases. A literature review was conducted to investigate the health hazards of PM2.5 ,particularly its impact on oxidative stress and inflammatory response, therefore to provide evidence for further research.

关 键 词：大气细颗粒物(PM2.5) 动物实验 氧化应激 炎症反应 

分 类 号：R122.7[医药卫生—环境卫生学]