心肌坏死生化标志物对多发性肌炎和非ST段抬高型心肌梗死的鉴别诊断价值  

The value of myocardial necrosis biochemical markers differentiating polymyositis from non-ST elevation myocardial infarction

作　　者：李宗庄[1] 吴强[1] 刘志琴[1] 韦方[1] 岳峰[1] 田野[1] 李福海[1] 刘启方[1] 张陈匀[1] 

机构地区：[1]贵州省人民医院心内科,贵阳550002

出　　处：《临床心血管病杂志》2017年第1期27-29,共3页Journal of Clinical Cardiology

摘　　要：目的:研究心肌坏死生化标志物在多发性肌炎和非ST段抬高型心肌梗死中的鉴别诊断价值。方法:回顾性分析我院近10年收治的49例多发性肌炎和发病12~24h入院的102例非ST段抬高型心肌梗死患者,收集其肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白Ⅰ(cTnI)等指标,并计算CK/CK-MB、CK/cTnI、CK-MB/cTnI比值,分析两组患者之间是否存在差异及2.5%、97.5%百分位数。结果:两组患者之间上述指标均有明显差异,但CK、CK-MB、CK/CK-MB三项指标两组之间数据重叠较多,cTnI、CK/cTnI、CK-MB/cTnI3项指标两组之间无数据重叠。结论:cTnI和CK/cTnI、CK-MB/cTnI比值是鉴别多发性肌炎和非ST段抬高型心肌梗死的重要生化指标。Objective：To explore the value of myocardial necrosis biochemical markers differentiating polymyositis from acute non-ST elevation myocardial infarction.Method：This investigation retrospected 49 cases diagnosed as polymyositis and 102 cases suffered from acute non-ST elevation myocardial infarction who has been hospitalized in our hospital,collected the CK,CK-MB and cTnI value and calculated the CK/CK-MB,CK/cTnI,CKMB/cTnI ratio,finally analyzed the differention between both groups.Result：All above variables showed statistically differentiation between both groups,but there were more the major overlaps between CK,CK-MB,CK/CKMB,and no other three variables,cTnI,CK/cTnI and CK-MB/cTnI ratio.Conclusion：cTnI,CK/cTnI and CKMB/cTnI ratio were the important biochemistry variables differentiating polymyositis from acute non-ST elevation myocardial infarction.

关 键 词：肌酸激酶 肌酸激酶同工酶 心肌肌钙蛋白I 多发性肌炎 非ST段抬高型心肌梗死 

分 类 号：R542.2[医药卫生—心血管疾病]