纤维支气管镜肺泡灌洗术治疗儿童难治性支原体肺炎疗效分析  

The effect of fiberoptic bronchoscopy and bronchoalveolar lavage in the treatment of refractory Mycoplasma pneumoniae pneumonia in children

作　　者：王娟[1] 孙军[1] 高长龙[1] 卢思广[1] 

机构地区：[1]连云港市第一人民医院儿科,江苏连云港222002

出　　处：《临床儿科杂志》2017年第1期16-18,共3页Journal of Clinical Pediatrics

摘　　要：目的评价纤维支气管镜支气管肺泡灌洗治疗难治性肺炎支原体肺炎的临床疗效。方法回顾性分析2015年2月至2016年2月因难治性肺炎支原体肺炎住院的55例患儿的临床资料。结果 55例患儿中,接受纤维支气管镜和支气管肺泡灌洗治疗的30例,为治疗组,另25例为对照组。治疗组和对照组仅有肺部片状影患儿分别为17例和13例,经治疗后吸收好转率分别为100%和69.2%,两组差异有统计学意义(P=0.026);治疗组总有效率为96.7%,高于对照组的64.0%,差异有统计学意义(P=0.006);治疗组的住院时间和平均治疗费用均短于对照组,差异有统计学意义(P<0.01);治疗组未出现严重并发症。结论纤维支气管镜支气管肺泡灌洗加局部应用药物治疗难治性支原体肺炎的效果明显,无严重不良反应。Objective To evaluate the clinical effects of fiberoptic bronchoscopy and bronchoalveolar lavage in the treatment of refractory Mycoplasma pneumoniae pneumonia. Method The clinical data of 55 children with refractory Mycoplasma pneumoniae pneumonia were retrospectively analyzed during February 2015 to February 2016. Results Among those 55 children, 30 cases who received the treatment of bronchoscopy and bronchoalveolar lavage were assigned to treatment group, and the other 25 cases were assigned to control group. 17 children in treatment group and 13 children in control group had lung lamellar shadow. After treatment, the improvement rates were 100% and 69.2% in treatment group and control group, respectively. There was significant difference between two groups （P=0.026）. The total effective rate in treatment group was 96.7%, which was significantly higher than that of control group （64.0%） （P=-0.006）. The length of hospital stay were significantly shorter and average treatment fee were significantly lower in treatment group than those in control group （P〈0.01）. There were no severe adverse reactions in treatment group. Conclusion The effects of fiberoptic bronchoscopy and bronchoalveolar lavage with local application of drug were remarkable in the treatment of refractory mycoplasma pneumonia, and there were no severe adverse reactions.

关 键 词：支气管肺泡灌洗 肺炎支原体 纤维支气管镜 儿童 

分 类 号：R725.6[医药卫生—儿科]