脑室出血伴脑积水单双侧脑室外引流效率比较  

Comparison of drainage efficiency between unilateral and bilateral external ventricular drainage in intraventricular hemorrhage with hydrocephalus

作　　者：綦斌[1] 左程[1] 常鹏飞[1] 李明[1] 时敬国 鲁质成[1] 王长坤[1] 

机构地区：[1]吉林大学第一医院神经血管病外科,长春130021

出　　处：《中华实验外科杂志》2017年第1期134-136,共3页Chinese Journal of Experimental Surgery

基　　金：吉林省科技发展计划项目（20160414039GH）

摘　　要：目的探讨单/双侧脑室外引流在治疗脑室出血伴梗阻性脑积水患者中的引流效率差异。方法总结经额角单/双侧脑室外引流术治疗56例脑室出血的患者资料，计算两组的血肿清除率、引流管放置时间、每日引流量、尿激酶注入次数、重症加强护理病房（ICU）住院时间，并进行相应统计学分析。结果单侧组、双侧组血肿清除率分别为（74.6±8.7）%、（78.5±12.5）%，两组比较差异无统计学意义（t＝1.308，P＝0.196）；单侧组、双侧组每日引流量分别为（124.6±40.2）、（139.6±41.7） ml，两组比较差异无统计学意义（t＝1.353，P＝0.182）；单侧组、双侧组平均尿激酶注入次数分别为（4.42±1.26）、（4.06±1.39），两组比较差异无统计学意义（t＝0.998，P＝0.323）；单侧组、双侧组ICU住院时间分别为（10.6±3.6）、（13.3±5.0） d，两组比较差异有统计学意义（t＝2.243，P＝0.029）；单侧组、双侧组引流管放置时间分别为（5.0±1.7）、（6.6±2.2） d，两组比较差异有统计学意义（t＝2.959，P＝0.005）。结论双侧组并不能提高血肿清除率，缩短带管时间、减少尿激酶使用次数、降低ICU住院时间。Objective To explore the differences of the drainage efficiency between unilateral external ventricular drainage and bilateral external ventricular drainage in surgical treatment of intraventricular hemorrhage.Methods The clinical data of 56 patients with intraventricular hemorrhage treated by unilateral and bilateral external ventricular drainage were retrospectively analyzed. 24 cases were treated by unilateral external ventricular drainage （unilateral group）, 32 cases were treated by bilateral external ventricular drainage （bilateral group）. The hematoma clearance rate, duration of catheter drainage, the average daily cerebrospinal fluid （CSF） drainage volume, the times of injecting the urokinase and the average hospital days in the intensive care unit （ICU） were recorded, and compared between two groups.Results In the group of unilateral drainage tube and group of bilateral drainage tube, the clearance rate of hematoma was （74.6±8.7）% and （78.5±12.5）%, comparison between the two groups was not statistically significant（t=1.308, P=0.196）; the daily CSF drainage volume was （124.6±40.2） ml and that was （139.6±41.7） ml, comparison between the two groups was not statistically significant（t=1.353, P=0.182）; the times of injecting the urokinase was （4.42±1.26） and （4.06±1.39）, comparison between the two groups was not statistically significant （t=0.998, P=0.323）; the hospital stay in the ICU was （10.6±3.6） days and （13.3±5.0） days respectively, there was a significant difference between the two groups （t=2.243, P=0.029）. The duration of catheter drainage in group of unilateral drainage tube was （5.0±1.7） days, and that was （6.6±2.2） days in group of bilateral drainage tube, and there was significant difference between the two groups （t=2.959, P=0.005）.Conclusion The bilateral external drainage can not improve the hematoma clearance rate, reduce the times of injecting the urokinase and lower the hospitalization days in the ICU of th

关 键 词：脑室出血 脑室外引流术 血肿清除率 

分 类 号：R651.1[医药卫生—外科学]