马蓝种质资源研究进展  

Progress on germplasm resources of Baphicacanthus cusia(Nees) Bremek

作　　者：周正[1] 郭志英[1,2] 谭何新[1] 刘佳颖[1] 刁勇[2] 张磊[1] 

机构地区：[1]第二军医大学药学院药用植物学教研室,上海200433 [2]华侨大学生物医学学院,福建泉州362021

出　　处：《药学实践杂志》2017年第1期1-4,16,共5页Journal of Pharmaceutical Practice

基　　金：国家自然科学基金-促进海峡两岸科技合作联合基金资助项目(U1405215);第二军医大学大学生创新实践课题-马蓝转录组测序数据分析及关键基因筛选(F2015094)

摘　　要：马蓝,广泛分布于我国西南、华南及华东地区,是重要的爵床科药用植物。由其茎、叶加工而成的青黛,以福建产品质最佳,被誉为建青黛,是福建道地药材。马蓝的根入药称南板蓝根,与青黛一起同为《中华人民共和国药典》药材品种。青黛及其原植物马蓝的指标性成分靛玉红(indirubin)是具有抗白血病功效的中成药"黄黛片"及"当归龙荟丸"的主要活性成分。笔者主要综述了马蓝种质资源的分布、生物学特征、栽培技术和分子生物学等国内外研究进展,并提出了马蓝种质资源面临的主要问题,为马蓝及青黛的相关研究与应用提供参考依据。Baphicacanthus cusia, widely distributed in the Southwest, Southern and Eastern regions of China, is an important medicinal plant of Acanthaceae family. Indigo made from stem and leaf of Baphicacanthus cusia in Fujian has the best quality in China, and is known as ＂Jian Indigo naturalis＂, which is the genuine medicinal of Fujian Province. The rhizoma of Baphicacanthus cusia could be used as medicine, called ＂Nanbanlangen＂, which together with indigo were included in the ＂Chi- nese Pharmacopoeia＂. Indigo and its original plant both contain indirubin, which has anti-cancer activity. Indirubin is an active ingredient of Huangdai Plan and Danggui Longhui Wan, two kinds of traditional Chinese medicine, which have been successful- ly used in the treatment of malignancies such as chronic myelogenous leukemia. The international advances in the biological characteristics, genetic diversity, cultivation technology and molecular biology of Baphicacanthus cusia germplasm resources were summarized. The main problems in Baphicacanthus cusia germplasm resources research are indicated, which could pro vide references for the further study and application of Baphicacanthus cusia germplasm resources.

关 键 词：马蓝 种质资源 生物学特性 栽培技术 遗传多样性 

分 类 号：R282.71[医药卫生—中药学]