鸡骨草与毛鸡骨草挥发油及脂肪酸成分的比较分析  

Comparative analysis of essential oil and fatty acid constituents of Abrus cantoniensis and Abrus mollis

作　　者：肖晓[1] 许重远[2] 杨德俊[1] 黄宝康[1] 

机构地区：[1]第二军医大学药学院,上海200433 [2]南方医科大学南方医院,广东广州510515

出　　处：《药学实践杂志》2017年第1期39-42,共4页Journal of Pharmaceutical Practice

基　　金：国家自然科学基金-广东联合基金项目重点项目(U1401226)

摘　　要：目的对鸡骨草和毛鸡骨草的挥发油及脂肪酸成分进行比较分析,为鸡骨草的品质评价及资源的进一步开发利用提供科学依据。方法采用水蒸馏的方法提取挥发油,95%乙醇提取物用石油醚萃取并经硅烷衍生化,采用气相色谱-质谱联用仪(GC-MS)进行挥发油及脂肪酸成分分析。NIST质谱标准库检索。结果在鸡骨草与毛鸡骨草挥发油中分别鉴别出42和33个化合物,各占总挥发油的56.76%和63.45%。(±)-α-乙酸松油酯为两者共有的主要成分。从脂肪酸成分中分别鉴别出13和14个化合物。鸡骨草与毛鸡骨草在挥发油与脂肪酸的成分组成方面存在明显区别。结论鸡骨草和毛鸡骨草的挥发油及脂肪酸成分GC-MS分析结果可为研究它们的活性成分及鸡骨草药材的综合利用与质量评价提供科学依据。Objective To utilize and evaluate the resources of Abrus cantoniensis Hance （AC） and Abrus mollis Hance （AM） by analyzing and comparing their essential oils and fatty acids. Method The essential oils of AC and AM were extracted with the hydro distillation method. Fatty acids were obtained by petroleum ether extraction of the 95 % ethanol concentrate. Fatty acid extract was further reacted with BSTFA for GC-MS analysis. Components were identified by searching NIST MS library. Result Forty two and thirty-three chemical constituents were identified from the essential oil of AC and AM respec tively, which accounted for 56.76 ~ and 63.45 ~ of their volatile components. （±）-a-terpinyl acetate are the common essential oils found in both AC and AM. Thirteen and fourteen chemical constituents were identified from the fatty acid extract of AC and AM respectively. AC and AM have different chemical components and compositions. Conclusion Our results provide a scientific basis for the bioactivities, quality control and resource utilization of AC and AM.

关 键 词：鸡骨草 毛鸡骨草 挥发油 脂肪酸 气相色谱-质谱联用仪 比较分析 

分 类 号：R284.1[医药卫生—中药学]