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作 者:原艳明[1] 王仲元[2] 翟守恒[1] 安慧茹[2] 杨帆[1]
机构地区:[1]解放军第264医院感染科,太原030001 [2]解放军309医院结核三科
出 处:《中国药物与临床》2017年第1期25-27,共3页Chinese Remedies & Clinics
摘 要:目的评价临床特征、实验室及影像学检查在结核性胸膜炎(TBP)、恶性胸腔积液(MPE)、肺炎旁积液(PPE)早期诊断中的价值。方法回顾性分析2012年1月至2013年12月解放军第309医院结核三科确诊的154例TBP、15例MPE、13例PPE患者的临床特征、实验室及影像学检查结果。结果发病年龄MPE>PPE>TBP。胸腔积液量MPE组(2 247±1 872)ml与TBP(1 296±1 118)ml、PPE组(828±1 025)ml比较,差异有统计学意义(P<0.05)。胸腔积液糖TBP组(5.1±2.5)mmol/L,与MPE及PPE组(7.1±2.3)mmol/L、(7.2±3.3)mmol/L比较,差异有统计学意义(P<0.05)。胸腔积液蛋白含量MPE组(37±11)g/L与TBP组(46±7)g/L、PPE组(47±5)g/L比较,差异有统计学意义(P<0.05)。胸腔积液CA125 MPE组(1 116±677)ng/ml与TBP组及PPE组(574±491)ng/ml、(796±503)ng/ml比较,差异有统计学意义(P<0.05)。结论年龄,胸腔积液量,胸腔积液糖、蛋白,血及胸腔积液CA125水平对于TBP和非结核性胸腔积液的鉴别诊断有意义。Objective To evaluate the value of clinical charateristics, laboratory and radiological examinations in the early diagnosis of tuberculous pleurisy (TBP), malignant pleural effusion (MPE) and parapneumonic effusion (PPE). Methods The clinical characteristics, laboratory and imaging findings of 154 cases of TBP, 15 of MPE and 13 of PPE, who were diagnosed in the Department of Tuberculosis, No.309 Hospital of Liberation Army between January 2012 and December 2013, were retrospectively analyzed. Results The age of onset was MPE〉PPE〉TBP. There was statistically significant difference in the pleural fluid volumebetween the MPE group [(2 247±1 872) ml] and the TBP group [(1 296±1 118) ml] and PPE group [(828±1 025) ml], respectively (P〈0.05). There was statistically significant difference in thepleural fluid glucose between the TBP group [(5.1±2.5) mmol/L] and the MPE group and PPE group [(7.1±2.3) mmol L, (7.2±3.3) mmol/L], respectively (P〈0.05). There was statistically significant difference in the content ofpleural fluid protein between the MPE group [(37±11) g/L] and the TBP group and PPE group [(46±7) g/L, (47±5) g/L], respectively (P〈0.05), There was statistically significant difference in the pleural fluid CA125 level between the MPE group [(1 116±677) ng/ml] and the TBP group and PPE group [(574±491) ng/ml, (796±503) ng/mll, respectively (p〈0.05). Conclusion The age, pleural fluid volume, pleural fluid glucose, pleural fluid protein, blood and pleural fluid CA125 level are significant for the differential diagnosis of TBP and non-tuberculous pleural effusion.
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