亚临床甲状腺功能减退症与2型糖尿病血管并发症的关系  

Relationship of Subclinical Hypothyroidism with Vascular Complications in Patients with Type 2 Diabetes Mellitus

作　　者：邓英英[1] 邱琳[1] 雒晓春[1] DENG Yingying QIU Lin LUO Xiaochun.(Department of Endocrinology,the Affiliated Hospital of Inner Mongolia Medical University , Hohhot 010050, China)

机构地区：[1]内蒙古医科大学附属医院内分泌科,呼和浩特010050

出　　处：《医学综述》2017年第1期120-124,共5页Medical Recapitulate

基　　金：内蒙古自治区自然科学基金(2013MS11105)

摘　　要：亚临床甲状腺功能减退症(SCH)是临床常见疾病,其诊断依据实验室检查,临床症状不明显,易被忽略。SCH在2型糖尿病中的发生率升高,SCH通过影响血脂、纤维蛋白原、D-二聚体、血小板参数、胰岛素抵抗等因素增加2型糖尿病血管并发症的发生率。SCH是2型糖尿病血管病变的独立危险因素,临床医师应该建议2型糖尿病患者定期检查甲状腺功能,并重视患SCH的2型糖尿病患者血管病变情况,通过给予适量的左旋甲状腺素治疗SCH以减少2型糖尿病血管并发症的发生。Subclinical hypothyroidism（SCH） is a common clinical disease, and its diagnosis is based on laboratory examination, the clinical symptoms of which are not obvious and may be easily ignored. SCH may affect blood lipids, fibrinogen, D-Dimer,platelet parameters,insulin resistance and other factors to increase the incidence of type 2 diabetic vascular complications. SCH is an independent risk factor for vascular complications in type 2 diabetes mellitus, so clinicians should recommend regular examination of thyroid function for patients with type 2 diabetes, and attach importance to the vascular complications in patients with type 2 diabetes mellitus with SCH,give levothyroxine treatment for SCH and reduce the incidence of vascular complications in type 2 diabetes mellitus.

关 键 词：亚临床甲状腺功能减退症 2型糖尿病 纤维蛋白原 D-二聚体 胰岛素抵抗 

分 类 号：R581.2[医药卫生—内分泌] R589[医药卫生—内科学]