体外冲击波治疗早中期膝关节骨关节炎的近期临床疗效观察  

Observation on short term effect of extracorporeal shock wave for treating early and middle stage of knee osteoarthritis

作　　者：李涛[1] 宋奇志[1] 裴建祥[1] 王愉乐[2] 牛陵川[2] 

机构地区：[1]重庆市重钢总医院骨科,400081 [2]重庆医科大学附属第二医院康复科,重庆400010

出　　处：《重庆医学》2017年第3期338-340,共3页Chongqing medicine

基　　金：重庆市卫生计生委医学科研项目(20142154)

摘　　要：目的观察体外冲击波(ESW)治疗早中期膝关节骨关节炎的疗效及安全性。方法收集2013年2月至2015年4月早中期膝关节骨关节炎患者90例,分为塞来昔布组与ESW组。塞来昔布组接受2周塞来昔布(200mg,1次/天)治疗,两组均接受体外ESW治疗的操作流程,但塞来昔布组设备无能量输出。采用疼痛视觉模拟评分(VAS)、Lequene-Mery评分系统、WOMAC骨关节炎指数及不良事件判定治疗有效性及安全性。结果治疗后4周,静息状态下VAS评分改善情况两组差异无统计学意义,但ESW组负重情况下VAS评分的改善明显优于塞来昔布组(P<0.05);治疗后12周,ESW组在静息和负重情况下VAS评分的改善均明显优于塞来昔布组(P<0.05),同时ESW组Lequene-Mery及WOMAC的评分改善也明显优于塞来昔布组(P<0.05)。结论体外冲击波治疗早中期膝关节骨关节炎近期临床疗效优于单纯塞来昔布治疗组。Objective To observe the effect and safety of extracorporeal shock wave（ESW）therapy in treating early and middle stage of knee osteoarthritis.Methods Totally 90 patients with early and middle stage of knee osteoarthritis from February2013 to April 2015 were collected and randomly assigned to the celecoxib group and ESW group.The celecoxib group received the2-week celecoxib（200mg once daily）therapy.The two groups received the operational process of ESW therapy.But there was no energy output in the celecoxib group.The therapeutic effect and safety were evaluated with the Visual Analog Scale（VAS）,Lequene-Mery scoring system,Western Ontario,McMaster Universities Osteoarthritis Index（WOMAC）and adverse events.ResultsThe VAS score improvement under resting state had no statistical difference between the two groups,while the improvement of VAS score under weight-bearing state in the ESW group was significantly superior to that in the celecoxib group（P〈0.05）,meanwhile the improvement of VAS,Lequene-Mery and WOMAC scores in the ESW group were significantly superior to the celecoxib group（P〈0.05）.Conclusion The short term effect of ESW therapy in treating early and middle stage of knee osteoarthritis is better than that of the simple celecoxib group.

关 键 词：骨关节炎 膝 体外冲击波 疼痛视觉模拟评分 

分 类 号：R684.3[医药卫生—骨科学]