东莞厚街地区育龄妇女碘营养状况及妊娠中期甲状腺激素参考值的探讨  

Discussion Analysis Houjie area women of childbearing age and iodine nutrition trimester thyroid hormone reference value

作　　者：黄文彩[1] 邓黎[1] 陈载鑫[1] 付文金[1] 蒋友明[1] 方海畴[1] 王少波[1] 文海燕[1] 徐维利 HUANG Wencai DENG Li CHEN Zaixin FU Wenjin J IANG Youming FAGN Haitao WANG Shaobo WEN Haiyan XU Weili(Department of Clinical Laboratory, Houjie Hospital of Guangdong Medical University, Dongguan , Guangdong 523945, China Department of Clinical Laboratory, E Dong Medical Groupcity Hospital of Traditional Chinese Medicine, Huangshi, Hubei 435002, China)

机构地区：[1]广东医学院附属厚街医院检验科,广东东莞523945 [2]鄂东医疗集团市中医医院检验科,湖北黄石435002

出　　处：《国际检验医学杂志》2017年第2期160-162,共3页International Journal of Laboratory Medicine

基　　金：广东省东莞市科研立项资助项目(201510515000235)

摘　　要：目的了解东莞厚街地区育龄妇女碘营养状况,探讨该地区妊娠中期甲状腺激素参考值范围,为临床提供依据。方法随机抽取2014年6月至2015年8月该院产科门诊患者以及育龄妇女各240例,采用过氧乙酸四甲基联苯胺氧化显色法进行随机尿的尿碘含量测定;采集妊娠中期妇女静脉血进行甲状腺激素检测。结果检测出孕妇尿碘水平<100.0、≥100.0~<300.0μg/L的比例都比育龄妇女高,而碘尿水平≥300.0μg/L的比例比育龄妇女低,2组比较差异有统计学意义(P>0.05)。甲状腺激素的上限低于阎氏甲状腺激素标准;血清游离甲状腺素上限标准低于阎氏标准;血清游离三碘甲腺原氨酸上限与阎氏甲状腺激素标准基本相同。结论该地区的甲状腺激素参考值范围应以该地区就诊的妇女为研究对象,为诊断甲状腺激素提供明确标准,有效降低了误诊率,为准确发现和及时治疗甲状腺功能紊乱的患者提供可靠依据和有效的干预。Objective To investigate the nutritional status of women of reproductive age iodine Houjie region and explore the region trimester thyroid hormone reference value range,provide the basis for clinical practice.Methods 240 cases of pregnant women and women of childbearing age were randomly selected for each area Houjie,arsenic cerium catalytic urine iodine spectrophotometry method random urine iodine content in urine determination;women collected trimester blood thyroid hormone testing.Results Detect pregnant women urine iodine level〈100.0,≥100.0-〈300.0μg/L ratio were higher than women of childbearing age,and iodine in urine level≥300.0μg/L ratio was lower than women of childbearing age,the two groups had statistical significance（P〈0.05）.TSH limit under standard of Yanshi thyroid hormone;FT4ceiling below Yanshi standard;Upper limit of FT3 and Yanshi thyroid hormone standard basic same.Conclusion Reference value range of thyroid hormones in the region as the region of women as the research object,and to provide a clear standard for diagnosis of thyroid hormone,effectively reduce the misdiagnosis rate,for the accurate detection and timely treatment of patients with thyroid dysfunction provide a reliable basis and effective intervention.

关 键 词：妊娠期 碘营养状况 甲状腺激素 

分 类 号：R714[医药卫生—妇产科学] R446.1[医药卫生—临床医学]