补正续骨泡腾颗粒质量标准研究  

Quality Standard Research for Buzheng Xugu Effervescent Granule

作　　者：关雪峰[1] 田原[1] 樊晖[1] 张锡玮[1] 孙科峰[1] 杨永菊[1] 张宇鹏[2] 

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032 [2]辽宁中医药大学,辽宁沈阳110847

出　　处：《辽宁中医药大学学报》2017年第1期13-15,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：辽宁省教育厅杰出青年基金项目(LJQ2012082);辽宁中医药大学青蓝工程-杏林杰出青年项目

摘　　要：目的:建立补正续骨泡腾颗粒的质量标准。方法:采用显微鉴别法对方中鹿茸进行显微定性鉴别,采用薄层色谱法对方中制何首乌、合欢花、骨碎补进行定性鉴别,采用高效液相色谱法测定续断中川续断皂苷Ⅵ含量。结果:薄层色谱斑点清晰,阴性液无干扰,显微特征明显,川续断皂苷Ⅵ在3.465~20.79μg范围内呈良好的线性关系(r=0.9999),平均回收率为99.8%。结论:该方法准确,专属性强,重复性好,可以作为控制补正续骨泡腾颗粒质量的方法。Objective：To establish the quality standard for Buzheng Xugu Effervescent Granule. Methods：TLC method was used to identify Polygoni Multiflori Radix Praeparata,Albiziae Flos,Drynariae Rhizoma,microscopic identification method was used to identify Cervi Cornu Degelatinatum. HPLC method was used to analyze concentrations of asperosaponin Ⅵ. Results：The TLC spots were clear without interference. The micro character was evident. The linear range of asperosaponin Ⅵ was 3.465-20.79μg,r=0.9999,average recovery was 99.8%. Conclusion：The method is accurate,specific,reproducible and can be used for quality control of Buzheng Xugu Effervescent Granule.

关 键 词：补正续骨泡腾颗粒 鹿茸 制何首乌 合欢花 骨碎补 川续断 皂苷Ⅵ 薄层色谱法 显微鉴别法 高效液相色谱法 

分 类 号：R284.2[医药卫生—中药学]