高原肝泡状棘球蚴病自体肝移植术后并发症的分析  

Analysis of postoperative complications after autologous liver transplantation in hepatic alveolar echinococcosis patients from plateau area

作　　者：高超[1] 叶成杰[2] 郭亚民[2] 吴纲[2] Gao Chao Ye Chengfie Guo Yamin Wu Gang(Qinghai University, Xining 810016, China)

机构地区：[1]青海大学,西宁810016 [2]青海省人民医院普外科

出　　处：《器官移植》2016年第6期449-453,共5页Organ Transplantation

摘　　要：目的分析高原肝泡状棘球蚴病(HAE)自体肝移植术后常见的并发症。方法回顾性分析6例行离体或半离体病肝切除+自体肝移植术的晚期HAE患者的临床资料。分析其主要术后并发症的特点。结果HAE肝移植术后并发症主要包括胆道并发症(4例)、腹腔出血(1例)、感染(3例),其中2例患者发生胆漏并腹腔感染,因感染性休克、多脏器功能衰竭死亡;1例患者出现腹腔出血,因失血性休克、弥散性血管内凝血死亡。胆道并发症和腹腔出血是导致患者死亡的主要原因。结论胆道并发症、腹腔出血、感染等术后并发症是影响HAE自体肝移植术患者预后的主要因素。Objective To analyze common postoperative complications after autologous liver transplantation in patients diagnosed with hepatic alveolar echinococcosis（ HAE） from plateau area. Methods Clinical data of 6 patients with advanced HAE undergoing ex-situ or partially ex-situ hepatectomy combined with autologous liver transplantation were retrospectively analyzed. Clinical characteristics of postoperative complications were analyzed. Results Postoperative complications mainly included biliary tract complications（ n = 4）,intra-abdominal hemorrhage（ n = 1）,infection（ n = 3）.Two cases presented with bile leakage complicated with intra-abdominal infection and died from infectious shock and multiple organ dysfunction syndrome. One patient had intra-abdominal hemorrhage and died from hemorrhagic shock and disseminated inravascular coagulation. Biliary tract complication and intra-abdominal hemorrhage were primary causes of mortality.Conclusions Biliary tract complication,intra-abdominal hemorrhage and infection are the main prognostic factors for HAE patients undergoing autologous liver transplantation.

关 键 词：高原 肝泡状棘球蚴病 自体肝移植 并发症 

分 类 号：R617[医药卫生—外科学] R383.33[医药卫生—临床医学]