高良姜及其化学成分调控物质能量代谢的药理学研究进展  

Pharmacological Research Review of Rhizoma Alpiniae Officmarum and Its Chemical Constituents in Regulating Substance and Energy Metabolism

作　　者：周莹[1] 朱卫丰[1] 章明[1] 吴超[1] 黄鑫[1] 郭政[1] 彭淑红[1] ZHOU Ying ZHU Weifeng ZHANG Ming WU Chao HUANG Xin GUO Zheng PENG Shuhong(Key Laboratory of Modem Preparation of Traditional Chinese Medicine （TCM） Differentiation and Development of Basic Theory of TCM, Jiangxi Jiangxi University of TCM, Nanchang 330004 Jiangxi, China） of Ministry of Education, Research Center for Province Key Laboratory of TCM Etiopathogenesis)

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室中医基础理论分化发展研究中心江西省中医病因生物学重点实验室,江西南昌330004

出　　处：《中药新药与临床药理》2017年第1期127-132,共6页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家自然科学基金项目(81260648)

摘　　要：中药寒热药性与物质能量代谢密不可分,高良姜能够通过影响物质能量代谢发挥其药理作用。本文从糖代谢、脂类代谢、氨基酸代谢、核苷酸代谢和线粒体生物氧化等几方面综述了近年来高良姜及其主要化学成分的药理学机制研究进展,探讨作为典型温热药的高良姜与物质能量代谢之间的关系,对其研究概况与研究方向进行总结、展望,以期为其他寒热中药的药理研究提供方向。Cold and hot natured properties of traditional Chinese medicine are closely correlated with substance and energy metabolism. And as a typical warm-hot herb,Rhizoma Alpiniae Officmarum plays the pharmacological role by affecting substance and energy metabolism. In this paper, we reviewed the progress of pharmacological actions of Rhizoma Alpiniae Officmarum and its chemical compositions in the aspects of glucose metabolism,lipid metabolism,amino acid metabolism, nucleotides metabolism, and mitochondrial biological oxidation. And the relationship of Rhizoma Alpiniae Officmarum with the metabolism of substance and energy was also discussed. The review is expected to provide a possible future direction for the pharmacological research of cold and hot Chinese herbal medicine.

关 键 词：高良姜 化学成分 物质代谢 能量代谢 作用机制 药理学 综述 

分 类 号：R285.5[医药卫生—中药学]