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作 者:李海滨[1]
出 处:《西南国防医药》2017年第1期20-22,共3页Medical Journal of National Defending Forces in Southwest China
摘 要:目的探讨替米沙坦联合卡维地洛治疗高血压合并糖尿病的疗效。方法 230例高血压合并2型糖尿病患者随机分为替米沙坦组、卡维地洛组、联合用药组,3组在常规降糖治疗基础上,分别予替米沙坦、卡维地洛、替米沙坦联合卡维地洛治疗,用药3个月后比较3组疗效。结果治疗后联合用药组收缩压、舒张压、心率均低于其他两组(P<0.05),且降压达标率高于其他两组(P<0.05);肾功能方面,联合用药组的3个肾功能指标均低于其他两组(P<0.05);而3组在不良反应发生情况上无统计学差异(P>0.05)。结论替米沙坦联合卡维地洛可以改善高血压合并糖尿病患者的血压、心率状况,而且能改善患者的肾功能,具有较好的疗效和安全性。Objective To explore the curative effects of telmisartan combined with carvedilol in the treatment of hypertension complicated with diabetes mellitus. Methods A total of 230 patients with hypertensive complicated with type-2 diabetes were randomly divided into telmisartan group, carvedilol group and combination group. On the basis of conventional antidiabetic treatment,the three groups were treated with telmisartan, carvedilol, and telmisartan combined with carvedilol. After three months of treatment,the curative effects among the three groups were compared. Results After the treatment, the systolic blood pressure, diastolic blood pressure and heart rate in the combination group were lower than the other two groups(P〈 0.05), and the blood pressure control rate was higher than that in the other two groups(P 〈0.05). For renal function, the three renal function indicators in the combination group were lower than those in the other two groups(P〈 0.05). There was no significant difference in adverse reactions among the three groups(P 〈0.05). Conclusion Telmisartan combined with carvedilol can improve the blood pressure, heart rate and renal function in patients 1with hypertension and diabetes mellitus, and has good efficacy and safety.
分 类 号:R554.1[医药卫生—血液循环系统疾病]
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