磁悬浮植入式心室辅助装置体外水力学及溶血实验  

Hydraulics and in Vitro Hemolysis Test of Implantable Magnetic Suspending Ventricular Assist Device

作　　者：吴广辉[1] 蔺嫦燕[1] 徐创业[1] 刘修健[1] 何玉娜 杨朋 陈琛 

机构地区：[1]首都医科大学附属北京安贞医院北京市心肺血管疾病研究所生物医学工程研究室,北京100029 [2]苏州同心医疗器械有限公司研发部,江苏苏州215125

出　　处：《中国医疗设备》2017年第1期14-17,共4页China Medical Devices

基　　金：国家高技术研究发展计划(863计划)(2012AA041605);国家自然科学基金(81670371)

摘　　要：目的测试一款小型磁悬浮植入式心室辅助装置的基本工作性能和体外溶血性能。方法通过体外水力学实验获得装置的基本工作性能;通过体外模拟实验(参照ASTM F1841标准)检测装置体外溶血性能。结果该磁悬浮植入式心室辅助装置主体血泵在3500 rpm左右能够提供5 L/min流量,100 mm Hg压力的辅助支持;体外实验标准溶血指数值为(0.0007±0.0003)mg/dL。结论体外水力学实验证实该装置工作性能稳定,可以满足成人心室辅助的需求,同时也具有较好的体外溶血性能。Objective To test the working performance and hemocompatibility of a small implantable magnetic suspending ventricular assist device. Methods The hydraulic pump performance has been tested through in vitro mock circulation loop experiments. The in vitro tests referring to ASTM F1841 standard were made to test the in vitro hemolytic performance. Results It turned out that the pump can deliver 5 L/min for pressures of 100 mmH g at a rotational speed of approximately 3500 rpm. The average normalized index of hemolysis values of the device was（0.0007±0.0003）mg/dL. Conclusion The in vitro hydraulics test indicated that the device works with stable performance and can meet the requirements of adult ventricular assist, meanwhile, it has good hemolytic performance.

关 键 词：心力衰竭 心室辅助装置 磁悬浮 水力学实验 溶血实验 

分 类 号：R318.11[医药卫生—生物医学工程]