酒石酸布托啡诺对剖宫产麻醉质量的影响  

Effect of butorphanol tartrate on quality of anesthesia for pregnant women undergoing cesarean delivery

作　　者：毛桂英[1] 李英[1] 

机构地区：[1]成都市第七人民医院麻醉科,四川成都610041

出　　处：《现代临床医学》2017年第1期30-31,34,共3页Journal of Modern Clinical Medicine

摘　　要：目的:探讨酒石酸布托啡诺对剖宫产孕妇麻醉质量的影响。方法:选择ASA分级Ⅰ~Ⅱ级术前无宫内窘迫的剖宫产者90例,按随机数字表法分为3组。A组在麻醉成功后、手术切皮开始前静脉给予酒石酸布托啡诺1 mg;B组在胎儿娩出后,静脉给予酒石酸布托啡诺1 mg;C组为空白对照组,不加静脉辅助药。观察3组产妇血压、心率、血氧饱和度,产妇术中镇静评分、牵拉反应、寒战反应,新生儿Apgar评分。结果:3组产妇血压、心率、血氧饱和度变化无显著性差异(均P>0.05);A组、B组镇静效果显著优于C组(均P<0.05),A组寒战反应显著低于B组、C组(均P<0.05),A组牵拉反应显著低于B组、C组(均P<0.05);3组均无明显恶心、呕吐、呼吸抑制等不良反应;3组新生儿Apgar评分无显著差异(P>0.05)。结论:酒石酸布托啡诺可安全用于剖宫产孕妇,对新生儿无不良反应,且提前用药能更有效地预防牵拉、寒战等不良反应发生,为剖宫产手术理想的麻醉辅助用药。Objective： To explore the effect of butorphanol tartrate on quality of anesthesia cesarean delivery. Methods： 90 women undergoing cesarean delivery with ASAgrade Ⅰ-Ⅱ and without distress were divided into three groups according to random mathematical method. Group A was intravenously given butorphanoltartrate of 1 mg before the incision of skin following the success of anesthesia; group B was of 1 mg following the delivery of fetus; group Cwas the control without venous adjuvant. Average heblood oxygen saturation,sedation score,traction reaction and shivering reaction of parturient and Apgar score of neonate werecompared between the three groups. Results： The average heart rate,blood pressure and blood oxygen saturation of parturientwere not significant different amongthe three groups. The sedative effect of group A and B was satisfactory, which was significantly superior to that of group C （ P 〈 0. 05 ）; the shivering reaction and traction reaction of group A were significantly slighter than those of group B and C; there were not obvious adverse reactions such as nausea,vomit and respiratory inhibition inthe three groups; moreover,no significant difference was found in neonatal Apgar scores among the three groups （P 〉0. 0 5） .Conclusion： Butorphanol tartrate can be safely used for cesarean delivery without adverse reactions to thedrug before operation can more effectively prevent traction,shivering and other adverse reactions. It anesthesia for cesarean delivery.

关 键 词：酒石酸布托啡诺 剖宫产 孕妇 麻醉质量 

分 类 号：R719.8[医药卫生—妇产科学] R614.2[医药卫生—临床医学]