凉山州2011-2015年哨点监测孕产妇HIV-1感染率及新发感染率结果分析  

Analysis of sentinel HIV-1 prevalence and incidence among pregnant women(PRG)in Liangshan Yi autonomous prefecture during 2011-2015

作　　者：杨洪[1] 肖琳[2] 谌茂刚 苏玲[1] 罗映娟[1] 叶黎[1] 魏东兵[1] 袁丹[1] 周更生[1] 刘红露[1] 余佳[1] 梁姝[1] Yang Hong Xiao Lin Shen Maogang Su Ling Luo Yingjuan Ye Li Wei Dongbing Yuan Dan Zhou Gengsheng Liu Honglu Yu Jian Liang Shu(Sichuan Center for Disease Control and Prevention, Chengdu, 610041 , China Liangshan Yi Autonomous Prefecture Center for Disease Control and Prevention)

机构地区：[1]四川省疾病预防控制中心,成都610041 [2]四川省凉山州疾病预防控制中心,四川西昌615000

出　　处：《中国艾滋病性病》2016年第12期1002-1004,共3页Chinese Journal of Aids & STD

基　　金：四川省卫生厅科研课题(130003)~~

摘　　要：目的在凉山州孕产妇人群中开展1型艾滋病病毒（HIV-1）新发感染检测,并估算该人群的HIV-1感染率和新发感染率,了解凉山州2011-2015年孕产妇人群HIV-1感染状况及防控策略探讨。方法用BED捕获酶免疫技术检测2011-2015年3个孕产妇哨点采集的HIV确证阳性样本,计算HIV-1在该人群中的感染率,并估算新发感染率,采用χ^2检验进行统计分析。结果 2011-2015年共对5486例血样进行HIV-1抗体筛查,确证阳性243例,HIV-1感染率4.43%;新发感染24例,新发感染率1.13%[95%可信区间（CI）：0.68~1.59]。χ^2趋势检验得到各年度新发感染率差异无统计学意义（χ^2=2.235,P=0.135）。结论 2011-2015年,凉山州孕产妇HIV-1感染率及新发感染率均处于较高水平,需进一步加强孕产妇人群的行为干预和监测工作。Objective To identify recent HIV-1infection,and to estimate HIV-1incidence,to explore measures and strategies for AIDS prevention and control among pregnant women in Liangshan Yi autonomous prefecture.Methods Samples were collected from 3PRG sentinel sites confirmed as HIV-1positive tested with BED-CEIA,and then the annual HIV-1prevalence and incidence were calculated and incidence was adjusted by McNermar method.Results 5486 serum samples were collected and tested with HIV antibody,of which 243 were confirmed as HIV-1positive,and 24 of them were identified as recent infections.The prevalence among PRG was 4.43%,incidence was 1.13%（95% CI：0.68-1.59）.There was no significant difference in HIV-1incidence（χ^2=2.235,P=0.135）.Conclusion During 2011-2015,the HIV-1prevalence and incidence are high in Liangshan,and enhancement of behavior intervention and surveillance on pregnant women is required.

关 键 词：1型艾滋病病毒 孕产妇 新发感染率 

分 类 号：R373.9[医药卫生—病原生物学]