急性休止期脱发的临床及皮肤镜表现  

Clinical and dermoscopic manifestations of acute telogen effluvium

作　　者：朱昭慧 叶艳婷[1] 曹慧[1] 凌云霞[1] 章星琪[1] 

机构地区：[1]中山大学第一附属医院皮肤性病科,广东广州510080

出　　处：《临床皮肤科杂志》2017年第2期89-92,共4页Journal of Clinical Dermatology

摘　　要：目的 :探讨急性休止期脱发(ATE)患者的临床及皮肤镜表现。方法 :回顾性分析15例ATE患者(患者组)的临床资料和皮肤镜表现,收集10例正常人毛发皮肤镜表现作为正常对照组。结果:15例ATE患者脱发起病急,为弥漫性脱发,全头拉发试验弱阳性,病程持续5~11周,平均7.3周。与正常对照组比较,患者组皮肤镜下表现为新生毳毛的数目增多及近皮面毛干的渐进性色素减退,色素减退毛干所占比例与病程长度呈负相关。脱落的毛干近毛根处亦有色素减退,毛根为杵状休止期和柱状排出期,排出期毛根部较为狭窄。病情恢复后,所有患者毛发恢复良好。结论:ATE临床特征明显,结合皮肤镜表现可初步诊断,皮肤镜下新生毳毛及色素减退毛干的比例能够提示病程长度。该病具有自限性,可在数月内完全恢复。Objective： To investigate the clinical and dermoscopic features of acute telogen effluvium （ATE）. Methods： Clinical manifestations and dermoscopic features of 15 patients with ATE were respectively analyzed, while ten healthy subjects served as normal controls. Results： All patients experienced acute and diffuse hair loss and had weakly positive hair pull tests. The duration of disease ranged from 5-11 weeks, with an average of 7.3 weeks. Compared with normal controls, the dermoscopic features of ATE included increased density of new vellus hairs, and progressive hypopigmentation of proximal part of the hair shaft. The proportion of hypopigmented hair shafts was negatively correlated with the disease course. The proximal part of the shed hair shaft was also hypopigmentation. Hair roots exhibited club hairs of telogen or columnar hairs of exogen. Hair roots became narrow during exogen. All subjects regained healthy hairs after recovery. Conclusion： Diagnosis of ATE can be made by the distinct set of clinical and dermoscopic features. The proportion of hypopigmented hair shafts and the density of newly grown vellus hairs could be used to predict the disease course. The disease is self-limited, and can be completely recovered within a few months.

关 键 词：急性休止期脱发 皮肤镜 毛根 色素减退 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]