2型糖尿病患者血清维生素D水平与叶酸、同型半胱氨酸的相关性  

Correlation of Serum Vitamin D Level with Folic Acid,Homocysteine in Type 2 Diabetes

作　　者：李永国[1] 

机构地区：[1]荆州市中心医院内分泌科,湖北荆州434020

出　　处：《贵州医科大学学报》2017年第1期94-96,共3页Journal of Guizhou Medical University

摘　　要：目的:探讨2型糖尿病血清中维生素D(VD)水平与叶酸(FA)、同型半胱氨酸(HCY)的相关性。方法:选取87例2型糖尿病患者作为观察组,90例健康体检者为对照组,测定并比较两组被检者血清中VD与FA、HCY水平,并比较这3种成分的相关性。结果 :观察组血清中VD、FA水平明显低于对照组,差异均具有统计学意义(P<0.05);而HCY水平明显高于对照组,差异具有统计学意义(P<0.05);两组被检者血清中VD与FA水平呈正相关,与HCY水平呈负相关,FA与HCY水平呈负相关。结论 :2型糖尿病患者VD含量较低,且血清中VD与FA、HCY水平有相关性。Objective： To investigate the correlation of vitamin D （VD） levels with serum folic acid （FA） levels and homocysteine （HCY） levels in type 2 diabetes. Methods： 87 patients with type 2 di- abetes were selected as the observation group, and 90 healthy subjects were selected as control group. The serum levels of VD, FA and HCY of the two groups were measured and compared, and the corre- lation between these 3 components was analyzed. Results： The serum levels of VD and FA in the ob- servation group were significantly lower than those in the control group （ P 〈 0.05 ）. The serum levels of HCY in the observation group were significantly higher than those in the control group （P 〈 0. 05 ）. VD levels was positively correlated with FA levels and negatively correlated with HCY levels , and FA lev- els was negatively correlated with HCY levels in the two groups. Conclusion： The levels of VD in pa- tients with type 2 diabetes was low, and the serum VD level was correlated with FA and HCY.

关 键 词：糖尿病 非胰岛素依赖型 维生素D 叶酸 同型半胱氨酸 

分 类 号：R587.1[医药卫生—内分泌]