侵袭性肺曲霉菌患者CT影像学与肺泡灌洗液半乳甘露聚糖检测阳性之间关系  

Relationship of CT imaging features and positive bronchoalveolar galactomannan for invasive pulmonary aspergillosis

作　　者：龚正[1] 龚萍 金柱[1] 张凌云[1] 王永全[1] 向光明[1] 高宝安[1] 陈世雄[1] 

机构地区：[1]三峡大学呼吸病研究所宜昌市中心人民医院,湖北宜昌443003 [2]宜昌市秭归县人民医院,湖北宜昌443600

出　　处：《中国临床医学影像杂志》2017年第1期27-29,共3页Journal of China Clinic Medical Imaging

基　　金：宜昌市医疗卫生科研基金项目(KFJ2013009)

摘　　要：目的 :观察侵袭性肺曲霉菌(Invasive pulmonary aspergillosis,IPA)感染患者CT影像学特征与肺泡灌洗液半乳甘露聚糖(Galactomannan,GM)实验阳性率之间的关系。方法:纳入120例确诊IPA感染患者,单因素Logistic回归分析CT侵犯肺叶数、空气新月征、晕轮征与肺泡灌洗液GM的关系。结果:IPA感染患者CT侵犯肺叶数、晕轮征与肺泡灌洗液GM实验阳性率显著相关。结论:CT影像学特征与肺泡灌洗液GM实验阳性率显著相关。Objective： To evaluate relationship between CT imaging features and positive bronchoalveolar galactomannan （GM） for invasive pulmonary aspergillosis （IPA）. Methods： One hundred and twenty patients with IPA were enrolled in this study. The levels of GM were measured in bronchoalveolar lavage （BAL）. Univariate logistic regression analysis was performed with GM in BAL and involved lung lobe number, existence of air crescent sign and halo sign. Result： The positive rate of GM in BAL is correlated with the number of involved lung lobes and existence of halo sign on CT. Conclusion： GM in BAL may be an important marker for diagnosing IPA, and GM in BAL is correlated with CT features.

关 键 词：曲霉菌病 支气管肺泡灌洗液 体层摄影术 螺旋计算机 

分 类 号：R563[医药卫生—呼吸系统] R519.8[医药卫生—内科学]