两种型号γ计数器测量正电子核素^(89)Zr的应用研究  

Application Study of 2 types of γ Counter Measurement of Positron Emission ^(89)Zr

作　　者：邹美芬[1] 徐栋[1] 钦晓峰[1] 潘栋辉[1] 徐希杰[1] ZOU Mei -fen XU Dong QING Xiao - feng PAN Dong - hui XU Xi - jie.(Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine,Jiangsu Institute of Nuclear Medicine. Wuxi 214063 China.)

机构地区：[1]江苏省原子医学研究所,卫生部核医学重点实验室,江苏省分子核医学重点实验室,江苏无锡214063

出　　处：《中国辐射卫生》2016年第6期735-738,共4页Chinese Journal of Radiological Health

基　　金：国家自然基金项目(81401450)

摘　　要：目的 PE公司两种型号γ计数器测定正电子核素^(89)Zr放射性强度的应用比较。方法用PE公司2480 WIZARD2、Wallac1470 WIZARDγ计数器分别测定同一^(89)Zr样品的CPM,计算cpm均值分别建立标准曲线,对每个样品的实际测量耗时、本底计数、精密度、重现性及相对测量效率等性能指标进行比较研究。结果当2480 WIZARD2、Wallac1470 WIZARDγ计数器的测量时间均设置为12 s时,每管的实际测量耗时分别为29.5 s和13.8 s。^(89)Zr的放射性活度在37~3.7×10~5Bq范围内2种型号γ计数器测量cpm值线性关系良好,回归方程分别为:y(cpm)=227.09x(Bq),R2=1和y(cpm)=14.04x(Bq),R^2=0.9995。最低检测限均为37 Bq。在待测样品总强度达7×3.7×10~5Bq时计数^(89)Zr初次本底值(cpm)分别为4263±45和2589±240。精密度分别为:0.63和0.98。重现性试验的RSD分别为:2.51和6.33。γ计数器测量^(89)Zr的相对效率分别为:44.59%和23.21%。结论 PE公司两种型号γ计数器操作简单、准确、灵敏,适用于^(89)Zr的放射性强度测定;总体测量效果和主要性能指标2480明显优于1470。Objective To compare the application of 2 types of γ counter^89Zr in the determination of the radioactive intensity of positron emission PE. Methods With PE company 2480 WIZARD2,Wallac1470 wizard γ counter samples of the same ^89Zr cpm were measured,cpm were calculated,respectively to establishv the standard curve. Comparison study was made for the practical measurements of each sample,the background count,precision,reproduce and relative measurement efficiency performance. Results When the measurement time of 2480 Wallac1470,WIZARD WIZARD2 γ counter was set to 12 seconds,the actual measurement time of each tube was 29. 5 and 13. 8 seconds respectively. The radioactive activity of^89Zr in the37 - 3. 7 × 10^5 Bq range two model gamma counter measurement cpm linear relationship is good. The regression equation is： y（ cpm） = 227. 09x（ Bq）,R^2= 1 and y（ cpm） = 14. 04x（ Bq）,R^2= 0. 9995. The lowest detection limits both were 37 Bq.The initial value of the counter^89Zr（ cpm） was 4263 ± 45 and 2589 ± 240,respectively. When the total strength of the sample to be measured was 7 × 3. 7 × 10^5 Bq,the precision is 0. 63 and 0. 98 respectively. Reproducibility tests of RSD were： 2. 51 and 6. 33. The relative efficiencies of^89Zr for γ counter measurement were 44. 59% and 23. 21% respectively. Conclusion The 2 types of PE γ counter is simple,accurate and sensitive,and can be used for the determination of the radioactive intensity of^89Zr. The overall measurement results and most of the performance indicators 2480 are significantly better than 1470.

关 键 词：γ计数器 两种型号 正电子核素 相对测量效率 89Zr 

分 类 号：R817[医药卫生—影像医学与核医学]