内消瘰疬片联合聚桂醇注射液治疗甲状腺囊肿的疗效观察  

Clinical observation of Neixiao Luoli Tablets combined with Lauromacrogol Injection in treatment of thyroid cyst

作　　者：刘文[1] 

机构地区：[1]绵阳市中心医院,四川绵阳621000

出　　处：《现代药物与临床》2016年第12期1959-1962,共4页Drugs & Clinic

摘　　要：目的观察内消瘰疬片联合聚桂醇注射液治疗甲状腺囊肿的临床疗效。方法选取绵阳市中心医院2015年1月—2015年12月收治的甲状腺囊肿患者106例,随机分为对照组和治疗组,每组各53例。对照组患者按抽吸囊液量的1/8于囊腔内注入聚桂醇注射液,根据囊肿缩小情况每7天治疗1次,共治疗1-3次。治疗组在对照组的治疗基础上口服内消瘰疬片,4片/次,2次/d。两组均连续治疗12周。观察两组临床疗效,比较两组治疗前后促甲状腺激素（TSH）、血白细胞计数（WBC）、丙氨酸转氨酶（ALT）指标水平变化。结果治疗后,对照组和治疗组总有效率分别为81.13%和94.34%,两组总有效率比较差异具有统计学意义（P〈0.05）。治疗后,同组及组间TSH、WBC和ALT指标水平比较差异均无统计学意义。结论内消瘰疬片联合聚桂醇注射液治疗甲状腺囊肿疗效确切,症状改善明显,具有一定的临床推广应用价值。Objective To observe the clinical curative effect ofn Neixiao Luoli Tablets combined with Lauromacrogol Injection in treatment of thyroid cyst. Methods Patients （106 cases） with thyroid cyst in Mianyang Central Hospital from January 2015 to December 2015 were randomly divided into the control and treatment groups, and each group had 53 cases. The patients in the control group were intra capsular iv administered with Lauromacrogol Injection, the dosage was equal to 1/8 of cystic fluid volume, 1 time every 7 d according to the situation of cyst narrowing, and total treatment for 1 - 3 times. The patients in the treatment group were po administered with Neixiao Luoli Tablets on the basis of the control group, 4 tablets/time, twice daily. Patients in two groups were treated for 12 weeks. After treatment, the clinical efficacy was evaluated, and TSH, WBC, and ALT level in two groups was compared. Results After treatment, the clinical efficacy in the treatment group was 94.34%, which was significantly higher than that （81.13%） of the control group, and there were differences between two groups （P 〈 0.05）. There was no significant difference on the levels of TSH, WBC, and ALT in the same group and between two groups. Conclusion Neixiao Luoli Tablets combined with Lauromacrogol Injection has a significant curative effect in treatment of thyroid cyst, can significantly improve the symptoms, which has a certain clinical application value.

关 键 词：内消瘰疬片 聚桂醇注射液 甲状腺囊肿 促甲状腺激素 谷丙转氨酶 

分 类 号：R977[医药卫生—药品]