急性百草枯中毒相关信号通路的研究进展  

Research progress on the signaling pathway of acute paraquat poisoning

作　　者：陈威[1] 杨霞[1,2] 

机构地区：[1]广西中医药大学附属瑞康医院急诊科,南宁530011 [2]广西医科大学研究生学院

出　　处：《临床急诊杂志》2016年第12期976-979,共4页Journal of Clinical Emergency

基　　金：广西急诊与医学救援人才小高地、广西高校急诊医学重点实验室课题(No:GXJZ201503)

摘　　要：百草枯（Paraquat,PQ）,又称为对草快,克无踪,因对农作物无害且又具有高效灭草的作用,故在我国被广泛应用于农业生产,但由于PQ对人畜均有极强的毒性,加之中毒后缺乏特效解毒剂及有效的治疗措施,因此中毒后病死率极高,Paraquat（PQ）is one of the most widely used herbicides in the world which can cause the injuries of the lung,kidney,liver and other vital organs,and the major accumulation are the lung and kidney.Owing to the lack of the specific antidote,PQ has a reputation of high mortality,and the early stage death is associated with lung injury.The mechanism of the paraquat poisoning is still not clear,so the article reviews the research progress on the mechanism of paraquat poisoning through the signaling pathway.

关 键 词：急性百草枯中毒 信号通路 机制 

分 类 号：R595.4[医药卫生—内科学]