冠心病患者HCY和凝血指标之间的关联分析  

Correlation Between HCY and Blood Coagulation Indexes in Elderly Patients With Coronary Heart Disease

作　　者：许亮亮[1] 张锋莉[2] 

机构地区：[1]南通市中医院检验科,江苏南通226001 [2]南通市中医院心内科,江苏南通226001

出　　处：《中国卫生标准管理》2016年第24期147-148,共2页China Health Standard Management

摘　　要：目的探讨冠心病患者血浆同型半胱氨酸（HCY）和凝血指标的相关性。方法选取本院32例冠心病患者设为观察组,参照Gensini积分将其分组即A组（0~20分）、B组（20~30分）、C组（超过40分）;另选取同期心电图为阴性、无冠心病症状的32例为对照组;均行常规检查,分析检查结果。结果 A组Fib指标（除却其他指标）显著高于对照组,P〈0.05;观察组的HCY和Fib、D-dimer的关系呈正相关。结论血HCY水平随着冠脉狭窄程度的增加而升高,损害凝血纤溶系统,促进冠脉内血栓合成,使病情加重。Objective To study the correlation of plasma homocysteine（HCY） and blood coagulation indexes in coronary heart disease patients. Methods 32 patients with coronary heart disease in our hospital were selected as observation group and divided into group A（0 ~ 20 points）,group B（20 ~ 30 points）,group C（above 40 points） with reference to Gensini score. 32 cases who had no symptoms of coronary heart disease and with ECG negative result during the same period were taken as control group. They were all adopted routine inspection,test results were analysed. Results Fib index（excluding other index） in the group A was significantly higher than that of control group,P〈0.05. HCY and Fib were positively correlated to D-dimer in observation group. Conclusion The level of blood HCY increases with the increase of coronary artery stenosis degree,it is damage to blood coagulation fibrinolytic system,and can promote the synthesis of intravascular thrombosis.

关 键 词：冠心病 HCY 凝血指标 

分 类 号：R541.4[医药卫生—心血管疾病]