中性粒细胞/淋巴细胞比值与急性心肌梗死患者急诊介入治疗术中发生无复流的关系  

Association between Neutrophils/lymphocyte ratio and no reflow in patients with STEMI undergone PCI

作　　者：谭萃妍 李松彪[1] 罗礼云[1] 

机构地区：[1]中山大学附属第五医院心血管内科,广东省珠海市519000

出　　处：《中国心血管病研究》2016年第12期1104-1108,共5页Chinese Journal of Cardiovascular Research

摘　　要：目的 通过检测急性ST段抬高型心肌梗死（STEMI）行急诊直接经皮冠脉介入治疗术（直接PCI）患者的中性粒细胞/淋巴细胞比值（N/L比值）,探讨N/L比值与PCI术中无复流发生风险的关系.方法 回顾性分析本院自2010年1月至2014年6月408例STEMI患者行直接PCI的临床和影像资料,其中102例出现无复流,306例血流正常,统计两组N/L比值水平差异,并分析发生无复流风险的独立危险因素.结果 无复流组N/L比值明显高于血流正常组,两组比较差异有统计学意义（4.8±1.6比3.0±1.9,P＜0.01）.N/L比值为无复流发生的独立危险因素（比值=2.183,95％可信区间：1.298～3.878,P＜0.01）.结论 N/L比值升高与急性ST段抬高型心肌梗死PCI术中无复流的发生有关.Objective The aim of this study was to evaluate the association between neutrophils/lympho- cyte ratio and the risk of no reflow in patients with acute ST segment elevation myocardial infarction undergone pereutaneous coronary intervention. Methods Clinical and angiographie data of 408 patients with STEMI after primary PCI were retrospectively analyzed between January 2010 and June 2014, no ref/ow was observed in 102 patients, coronary blood flow is normal in other 306 patients, neutrophils/lymphocyte ratio was measured in all patients. N/L ratio level difference was compared in this two groups, Logistic regression analysis was used to ana- lyze the independent risk factor of no reflow. Results N/L ratio level was significantly higher in the no reflow group than control group （4.8±1.6 vs 3.0±1.9, P〈0.01 ）. N/L ratio was the independent risk factor of no reflow （OR=2.183, 95%CI 1.298-3.878, P〈0.01）. Conclusion Our results suggest that N/L ratio is associate with no reflow in STEMI patients undergoing primary PCI.

关 键 词：无复流 急性ST段抬高型心肌梗死 中性粒细胞/淋巴细胞比值 经皮冠状动脉介入治疗 

分 类 号：R542.22[医药卫生—心血管疾病]