2013年江西省三个耐药监测点结核病耐药情况分析  

Drug resistance of Mycobacterium tuberculosis isolated from some areas of Jiangxi

作　　者：赵竟男[1] 何旺瑞[1] 邱林西[1] 彭小梅[1] 曾艳文[1] 黄锐[1] ZHAO Jing-nan HE Wang-rui QIU Lin-xi PENG Xiao-mei ZENG Yan-wen HUANG Rui.(Jiangxi Provincial Center for Disease Control and Prevention, Nanchang 330029, Jiangxi, Chin)

机构地区：[1]江西省疾病预防控制中心结核病预防控制所,江西南昌330029

出　　处：《疾病监测》2016年第12期1061-1063,共3页Disease Surveillance

基　　金：江西省卫生计生委科技计划(No.20156033)~~

摘　　要：目的分析江西省部分地区结核病的耐药情况,为该省耐药结核病防治提供参考依据和技术支持,评价结防工作成效。方法对纳入监测的活动性结核病患者的痰标本分离培养后进行药敏试验,以获得能够反映江西省活动性结核病患者初治耐药和复治耐药情况的基础数据。结果 283株分离株中,总耐药率27.21%,初治患者的总耐药率为23.21%,复治患者的总耐药率为47.83%。任一耐药以异烟肼耐药最多,占12.01%;耐多药11例,占3.89%。结论规范化治疗管理初见成效,应进一步加强耐药监测工作。Objective To understand the drug resistance of Mycobacterium（M.） tuberculosis in some areas of Jiangxi province and provide evidence for tuberculosis（TB） prevention and control and related evaluation.Methods The sputum samples collected from the active TB patients surveyed were used to culture M.tuberculosis for the drug susceptibility test.Results The overall drug resistant rate of M.tuberculosis was 27.21%,and the drug resistant rate was 23.21% in newly detected patients and 47.83% in retreat patient.The single drug resistant rate to isoniazid was highest（12.01%）,and multidrug resistance was detected in 11 cases（3.89%）.Conclusion The standardized TB treatment and management has achieved initial success,but it is still necessary to further strengthen the surveillance for drug resistant TB.

关 键 词：结核 耐药 监测 

分 类 号：R52[医药卫生—内科学]