Solitaire FR支架机械取栓联合5F Navien导管抽吸技术治疗大脑中动脉急性闭塞的效果分析  

Effect analysis of Solitaire FR stent mechanical thrombectomy combined with 5F Navien catheter aspiration technique for the treatment of acute middle cerebral artery occlusion

作　　者：李桂林[1] 杜世伟[1] 李静伟[1] 闫峰[1] 向思诗 陈健[1] 张鸿祺[1] Li Guilin Du Shiwei Li Jingwei Yan Feng Xiang Sishi Chen Jian Zhong Hongqi.(Department of Neurosurgery , Xuanwu Hospital, Capital Medical University, Beijing 100053, China)

机构地区：[1]首都医科大学宣武医院神经外科,北京100053

出　　处：《中国脑血管病杂志》2017年第1期37-42,共6页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的探讨Solitaire FR支架机械取栓联合5F Navien导管抽吸技术治疗大脑中动脉急性闭塞的安全性和有效性。方法回顾性连续纳入2016年2月至5月首都医科大学宣武医院神经外科接受Solitaire FR支架机械取栓联合5F Navien导管抽吸技术治疗的大脑中动脉急性闭塞患者(发病<6 h)11例的病例资料,记录患者年龄、性别、入院美国国立卫生研究院卒中量表(NIHSS)评分、脑梗死溶栓试验(TICI)分级、手术相关并发症、术后24 h NIHSS评分,术后90 d改良Rankin量表(mRS)评分。通过SPSS软件对治疗前后相关数据的差异进行分析。结果 11例大脑中动脉急性闭塞患者中,男7例,女4例,年龄44~78岁,平均(66±11)岁;术前及术后NIHSS评分分别为(18±3)、(8±4)分,治疗前后差异有统计学意义(t=5.327,P<0.01);均成功实现闭塞大脑中动脉的再通。术后90 d随访,患者预后良好(mRS 0~2分)7例。无严重的M1段内导管操作的相关并发症。结论初步经验显示,Solitaire FR支架机械取栓联合5F Navien导管抽吸技术治疗大脑中动脉急性闭塞是一种安全有效的血管内机械取栓方法。Objective To investigate the safety and effectiveness of Solitaire FR stent mechanical thrombectomy combined with 5F Navien catheter aspiration technique for the treatment of acute middle cerebral artery occlusion.Methods From February 2016 to May 2016,the case data of 11 consecutive patients with acute middle cerebral artery occlusion treated with Solitaire FR stent mechanical thrombectomy combined with 5F Navien catheter aspiration technique at the Department of Neurosurgery,Xuanwu Hospital,Capital Medical University were enrolled retrospectively.The age,gender,National Institutes of Health Stroke Scale（ NIHSS） score on admission,thrombolysis in cerebral infarction（ TICI） grade,operationrelated complications,NIHSS score at 24 h after operation,and modified Rankin Scale（ mRS） score at day90 after operation were documented.The relevant data differences before and after treatment were analyzed with the SPSS software.Results Among the 11 patients with acute middle cerebral artery occlusion,7 were men and 4 were women,the age ranged from 44 to 78 years,and the mean age was 66 ± 11 years.The preoperative and postoperative NIHSS scores were 18 ± 3 and 8 ± 4 respectively.There was significant difference before and after treatment（ t = 5.327,P〈0.01）.The recanalization of occluded middle cerebral artery achieved successfully.The follow-up at day 90 after operation,the good prognosis of the patients（ mRS 0-2） was in 7 cases.No complications associated with severe M1 segment catheter operation occurred.Conclusion The preliminary experience showed,Solitaire FR stent mechanical thrombectomy combined with 5F Navien catheter aspiration technique for the treatment of acute middle cerebral artery occlusion was a safe and effective endovascular mechanical thrombectomy method.

关 键 词：支架 导管插入术 梗塞 大脑中动脉 机械取栓 

分 类 号：R651.12[医药卫生—外科学]