应用Astogaph法对咳嗽变异哮喘的诊断评估  

Diagnostic evaluation of Astogaph for cough variant asthma

作　　者：吴小燕[1] 洪原城[1] 范洪涛[1] 郑宝聪 WU Xiao-yan HONG Yuan-cheng FAN Hong- tao ZHENG Bao-cong(the 180th Hospital of PLA, Quanzhou, Fujian 362000, China)

机构地区：[1]中国人民解放军第180医院(福建医科大学第180教学医院)呼吸内科,福建泉州362000

出　　处：《临床肺科杂志》2017年第3期503-505,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨应用Astogaph法检测对咳嗽变异哮喘的诊断评估。方法选取我院接诊的慢性咳嗽患者80例进行研究,入院后采取Astogaph法检测,根据检测后激发试验阳性(42例)与阴性(38例)分为两组,比较两组肺功能指标与激发试验结果。结果激发试验阳性组患者在第一秒用力呼气量(FEV_1)、用力肺活量(PEF)及FEV_1/FVC上均明显低于阴性组(P<0.05);同时,阳性组激发试验结果基础阻力与传导率下降斜率(SGrs)与阴性组比较也有明显差异(P<0.05)。结论 Astogaph法检测咳嗽变异哮喘有很好的诊断价值,激发试验阳性与阴性间肺功能有明显差异,可作为辅助诊断标准。Objective To evaluate the diagnostic value of Astogaph for cough variant asthma （CVA）. Methods 80 patients with chronic cough were divided into two groups by Astogaph assay, the positive group （42 ca- ses ） and the negative group （ 38 cases）. Their lung function and challenge test results were compared. Results The value of FEV1 , PEF and FEVI/FVC was significantly lower in the positive group than in the negative group （ P 〈 0. 05）. At the same time, there was significant difference in SGrs between the two groups （P 〈 0. 05）. Conclusion Astogaph assay has good diagnostic value on cough variant asthma, and there is significant difference between the positive and negative pulmonary function test.

关 键 词：咳嗽变异哮喘 Astogaph法 诊断 

分 类 号：R562.25[医药卫生—呼吸系统]