儿童Kimura病1例报道并文献复习  

Report and Literature Review: a Case of Child with Kimura Disease

作　　者：章俏雷[1] 方炳木[1] 刘永华[1] 曲志刚[1] 江锦红[1] 马光丽[1] Zhang Qiaolei Fang Bingmu Liu Yonghuang Qu Zhigang Jiang Jinhong Ma Guangli(Lishui People＇ s Hospital, Sixth Affiliated Hospital of Wenzhou Medical University, Zhejiang Lishui 323000, Chin)

机构地区：[1]丽水市人民医院温州医科大学附属第六医院,浙江丽水323000

出　　处：《儿科药学杂志》2017年第2期23-26,共4页Journal of Pediatric Pharmacy

摘　　要：目的:分析儿童Kimura病的临床特点,探讨儿童Kimura病的诊治方法及预后。方法:对我院2014年收治的1例儿童Kimura病进行报道,同时检索2005-2015年的中国医院知识总库(CHKD),收集资料完整的7例儿童Kimura病报道,对这8例Kimura病患儿的临床表现、实验室检查、治疗及预后进行综合分析。结果:儿童Kimura病主要表现为头颈部肿块、淋巴结肿大、大涎腺侵犯,外周血嗜酸粒细胞增多、血清Ig E水平升高,病灶边界不清无包膜,激素治疗有效,但容易复发。结论:Kimura病是一种罕见的、慢性的、病因不明的慢性炎性疾病,儿童Kimura病更加罕见,常表现为头颈部肿块,伴淋巴结肿大及大涎腺侵犯,手术、激素治疗有效,但容易复发。Objective： To analyze the clinical features of children Kimura disease and investigate its diagnosis,therapy and prognosis.Methods： One case admitted in our hospital in 2014 was reported. General knowledge base of Chinese Hospital from 2005 to 2015 was searched. There were 8 cases with complete clinical data. The clinical manifestation,laboratory examination,therapy and prognosis were analyzed. Results： Head and neck neoplasm,swelling lymph nodes and large salivary gland involvement,the increasing peripheral eosinophil count,the rising serum Ig E level were the clinical features of the children Kimura disease. The lesion boundary was not clear and had no envelope. The glucocorticoid therapy was effective,but easy to relapse. Conclusion： Children Kimura disease is a rare chronic inflammatory disorder of unknown etiology. It is often associated with regional lymphadenopathy. Though surgical resection,glucocorticoid therapy have good effects,but recurrence may occur.

关 键 词：儿童 KIMURA病 文献复习 

分 类 号：R725.5[医药卫生—儿科]