超声及CT诊断甲状腺良恶性结节的临床研究  

Clinical Study of Ultrasound and CT in Diagnosis of Benign and Malignant Thyroid Nodules

作　　者：黄雪[1] 夏红梅[1] 谭开彬[1] 张玥[1] HUANG Xue XIA Hong-mei TAN Kai-bin et al.

机构地区：[1]第三军医大学附属新桥医院超声诊断科,重庆400037

出　　处：《中国CT和MRI杂志》2017年第2期39-41,共3页Chinese Journal of CT and MRI

基　　金：国家自然科学基金资助课题(NO:30571570)

摘　　要：目的探讨超声及CT在鉴别诊断甲状腺良恶性结节中的临床应用价值。方法选取120例(138个结节)甲状腺结节患者为研究对象,均接受超声及CT检查,以病理检测结果为"金标准",评估CT、超声及CT联合超声检查在鉴别诊断甲状腺良恶性结节中的准确性、特异性、敏感性差异。结果 120例甲状腺结节患者确诊为良性者89例(74.2%)、恶性者31例(25.8%);CT联合超声检查正确诊断恶性结节27例,良性结节85例,诊断准确性为93.3%、特异性为95.5%、敏感性为87.1%,均显著高于单纯CT检查的80.3%、82.0%和77.4%及单纯超声检查的83.3%、86.5%和74.2%,差异具有统计学意义(P<0.05)。结论 CT联合超声检查可有效提升甲状腺良恶性结节鉴别诊断准确性,患者耐受程度高,对降低误诊及漏诊风险、提高诊疗效率等具有积极意义。Objective To investigate the clinical application value of ultrasound and CT in differential diagnosis of benign and malignant thyroid nodules. Methods 120 patients （138 nodules） with thyroid nodules were selected as study subjects and received ultrasound and CT examination. With the results of pathological examination as the golden standard, the differences inaccuracy, specificity and sensitivity between CT, ultrasonnd and CT combined with ultrasound in the differential diagnosis of benign and malignant thyroid nodules were evaluated. Results Among the 120 patients with thyroid nodules, there were 89 cases （74.2%） with benign nodules and 31 cases （25.8%） with malignant ones. There were 27 cases of malignant nodules and 85 cases of benign nodules correctly diagnosed by CT combined with ultrasound, and the diagnostic accuracy, specificity and sensitivity were 93.3% , 95.5% and 87.1%, respectively which were significantly higher than those of simple CT examination （80.3%, 82.0%, 77.4%） and simple ultrasound （83.3%, 86.5%, 74.2%） （P〈0.05）. Conclusion CT combined with ultrasound examination can effectively improve the accuracy of differential diagnosis of benign and malignant thyroid nodules. The tolerance of patients is high, which is of positive significance in redncing the risk of misdiagnosis and missed diagnosis and improving the efficiency of diagnosis.

关 键 词：超声 CT 甲状腺良恶性结节 甲状腺良恶性结节 

分 类 号：R581[医药卫生—内分泌]