痛风患者足部痛风石沉积特点的双能量CT研究  

Study of the Distribution Featuresof Tophus in Foot using Dual-energy Computed Tomography

作　　者：陈谦[1] 陈兴国[2] 冯源[1] 许权[1] 吴前芝[1] 沈敏宁[2] 殷信道[1] CHEN Qian CHEN Xing-guo FENG Yuan et al.(Department of P.adiology. Nanjing First Hospital, NanjingMedical University. Nanjing 210006, Jiangsu province, China)

机构地区：[1]南京医科大学附属南京医院放射科,江苏南京210006 [2]南京医科大学附属南京医院风湿免疫科,江苏南京210006

出　　处：《中国CT和MRI杂志》2017年第2期113-115,共3页Chinese Journal of CT and MRI

基　　金：2016年度南京医科大学科技发展基金项目;项目编号:2016NJMU069

摘　　要：目的应用双能量CT对足部痛风石常见沉积部位进行分析,并对痛风发病机制进行探讨研究。方法回顾性分析56例痛风患者的足部双能量CT扫描检查资料。将根据痛风石沉积部位分为关节组、韧带/肌腱组,并分别对其进行记录、分析。结果 56例患者中双能量CT共发现51例患者有痛风石沉积。关节组最常见受累部位为第一跖趾关节(75%,73/198),其次是踝关节(33.9%,32/198)。韧带/肌腱组中最常见受累部位依次是跟腱(39.3%,37/99)、腓骨肌腱(16.1%,14/99)。结论足部痛风石常见受累关节及韧带/肌腱分别为第一跖趾关节及跟腱,足部痛风石的沉积部位与特殊解剖部位、生物力学作用等有关。Objective To evaluate the distribution oftophus in foot using dual-energy CT （DECT）and to explore the pathogenesis of gout. Methods Fifty-six patients with gout had DECT scanning of both feet. The sites oftophus deposition were categorized into groups of joint, ligament/tendon and they were recorded and analyzed in order.Results The DECT scans showed tophus involving 51/56 （91.1%） patients. In the group of joint, gout affected the first metacarpophalangeal joint （75%, 73/198） mostly, followed bythe ankle joint （33.9%, 32/198）.In the group of tendon/ligament, Achillestendon was the most connnonly involved （39.3%, 37/99）, followed bythe peroneal tendons （16.1%, 14/99）. Conclusion In foot, tophus is commonly deposited at the first metacarpophalangeal joint and Achillestendon. The patterns of tophus deposition suggest that anatomical location, biomechanical strain or other local factors may contribute to the distribution of tophus.

关 键 词：双能量CT 痛风 痛风石 

分 类 号：R445.3[医药卫生—影像医学与核医学] R589.7[医药卫生—诊断学]