浅谈降压药——血管紧张素Ⅱ受体拮抗剂ARB  

Antihypertensive drugs--Angiotensin Ⅱ receptor blockers

作　　者：田海军[1] 刘海婷[2] 王晓明[2] 张华[2] TIAN Hai-jun LIU Hai-ting WANG Xiao-ming ZHANG Hua(Department of Veteran Cadres, PEA 161 Hospital, Wuhan 430010, Hubei, China Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi＇an 710032, Shaanxi, China)

机构地区：[1]解放军第161医院干部病房,湖北武汉430010 [2]第四军医大学西京医院老年病科,陕西西安710032

出　　处：《心脏杂志》2017年第1期120-122,126,共4页Chinese Heart Journal

基　　金：国家自然科学基金项目资助(81370928);陕西省社会发展科技攻关项目资助(2015SF095)

摘　　要：高血压是心脑血管疾病最常见的危险因素之一,而血管紧张素Ⅱ受体拮抗剂(angiotensin II receptor blockers,ARB)是作用于肾素-血管紧张素-醛固酮系统的常用抗高血压药。近年来,ARB广泛应用于临床,本文从ARB对心、脑、肾等靶器官的保护作用浅谈分析该类药物作为临床一线降压药物的原因。Hypertension is one of the most common cardiovascular disease risk factors and angiotensin II receptor blockers （ARB） are antihypertensive drugs acting on the renin-angiotensin-aldosterone system. In recent years, ARB drugs have been widely used in the clinical setting. This article analyzes the reasons why ARB drugs are clinically used as the first-line antihypertensive drugs by discussing the protective role of ARB for target organs such as in cardiovascular, cerebrovascular, and kidney diseases as well as diabetes.

关 键 词：血管紧张素Ⅱ受体拮抗剂 高血压 血管紧张素受体 

分 类 号：R541.3[医药卫生—心血管疾病]