生漆中漆酚单体分离、化学结构修饰及生物活性研究进展  

Progress on the Monomer Separation,Chemical Structural Modification and Biological Activity of Urushiol from Raw Lacquer

作　　者：周昊[1,2,3,4,5] 王成章[1,2,3,4,5] 邓涛[1,2,3,4] 陈虹霞[1,2,3,4] 陶冉[1,2,3,4] 

机构地区：[1]中国林业科学研究院林产化学工业研究所 [2]生物质化学利用国家工程实验室 [3]国家林业局林产化学工程重点开放性实验室 [4]江苏省生物质能源与材料重点实验室,江苏南京210042 [5]中国林业科学研究院林业新技术研究所,北京100091

出　　处：《生物质化学工程》2017年第1期44-50,共7页Biomass Chemical Engineering

基　　金：江苏省生物质能源与材料重点实验室基本科研业务费项目(JSBEM-S-201509)

摘　　要：漆酚化合物是具有C15或C17烃基侧链的邻苯二酚结构,侧链不饱和度为0~3。漆酚良好的抗肿瘤、抑菌和抗氧化活性使其受到越来越多的关注。对不同不饱和度烃基漆酚单体的分离方法进行了叙述,介绍了通过对漆酚的苯环或侧链烃基进行化学结构修饰这2种途径以获得结构相对稳定的漆酚衍生物,并阐述了漆酚单体及其衍生物的抗肿瘤、抗氧化、抑菌和抗病毒等生物活性。Urushiol possesses catechol structure with C15 or C17alkyl side chain. They consist of different alkyl phenols with the degree of unsaturation from 0 to 3. The potent antitumor,antimicrobial and antioxidant activities of urushiol have been greatly concerned. In this paper,the research progresses on separation method of different urushiol monomer are described. And the chemical structure modification of benzene ring and alkyl side chain urushiol to obtain stable urushiol derivatives are introduced.And then,the anti-tumor,antioxidant,antibacterial,antiviral activities of urushiol monomers and their derivatives are discussed.

关 键 词：生漆 漆酚 单体分离 结构修饰 生物活性 

分 类 号：TQ630.1[化学工程—精细化工]