急性心肌梗死患者的心率变异性特征分析  

Analysis on features of heart rate variability in patients with acute myocardial infarction

作　　者：白光辉[1] 张云强[2] 梁海青[2] 郭牧[2] 宋昱[2] 

机构地区：[1]天津医科大学研究生院,天津300070 [2]泰达国际心血管病医院CCU,天津300145

出　　处：《天津医科大学学报》2017年第1期56-58,共3页Journal of Tianjin Medical University

摘　　要：目的:探讨急性心肌梗死患者心率变异性(HRV)特征。方法:选择急诊心肌梗死患者190例,根据冠脉狭窄程度积分(Gensini评分)将其分为冠状动脉病变高分组、中分组、低分组。常规检测生化指标,进行24 h动态心电监测,记录HRV指标,分析比较各组间HRV指标差异有无统计学意义,同时比较HRV与心肌梗死部位相关性。结果:HRV指标ASDNN、RMSSD、SDNN和SDANN随着Gensini评分值升高而降低,低分组、中分组、高分组组间比较差异具有统计学意义(均P<0.05);Pearson相关分析显示HRV指标ASDNN、RMSSD、SDNN和SDANN与Gensini评分值呈负相关(P<0.05)。与非前壁心肌梗死相比,前壁心肌梗死患者HRV指标ASDNN、RMSSD、SDANN和SDNN较低,差异有统计学意义(P<0.05)。结论:急性心肌梗死患者HRV各指标与冠状动脉病变程度及心肌梗死部位有相关性。Objective： To explore features of heart rate variability （HRV） in patients with acute myocardial infarction. Methods： One hundred and ninety patients with myocardial infarction who underwent coronary angiography were analyzed and divided into three groups by Gensini scoring： low group（n=62）, middle group（n=64）, high group（n =64）. All cases underwent 24 hour ambulatory electrocardiogram and their biochemical indicators were detected. Finally, the clinical information was analyzed and compared. Results： ASDNN, RMSSD, SDNN and SDANN indices tended to decrease with the extent and severity of coronary artery lesion,and showed statistical differences among low group, middle group and high group （P〈0.05）. The index of HRV decreased as the severity of artery lesion increased （P〈O.05）. Anterior wall myocardial infarction had lower HRV in ASDNN,RMSSD SDNN and SDANN indices （ all P 〈0.05） than non-anterior wall myocardial infarction. Conclusion： The HRV may be related to the lesion degree of coronary artery and the location of myocardial infarction in patients with acute myocardial infarction.

关 键 词：心率变异性 急性心肌梗死 冠状动脉病变程度 

分 类 号：R542.22[医药卫生—心血管疾病]