血浆胎球蛋白A水平与急性心肌梗死的关系  

Association of Plasma Fetuin-A with Acute Myocardial Infarction

作　　者：沈亚萍 许浩 何国平[2] 许联红[3] 

机构地区：[1]江苏大学附属武进医院急诊科,江苏常州213000 [2]江苏大学附属武进医院急诊科心血管内科,江苏常州213000 [3]江苏大学附属武进医院中心实验室,江苏常州213000

出　　处：《医学临床研究》2017年第1期12-13,16,共3页Journal of Clinical Research

摘　　要：【目的】探讨中国常武地区汉族人群血浆胎球蛋白A（Fetuin—A）与急性心肌梗死（AMI）的相关性。【方法】采用酶联免疫吸附法检测86例AMI患者（观察组）和45例非冠心病（CAD）者（对照组）血浆Fe—tuin—A水平。【结果】观察组血浆Fetuin—A水平为（426．14±133．27）∥L，显著高于对照组（278．02±137．10）∥L，经Logistic回归分析校正CAD易患因素（年龄、性别、吸烟、高血压史、糖尿病史等的）影响后，其差异仍具有显著性（均P〈0．01）；线性回归分析显示传统CAD危险因素中仅年龄与Fetuin—A水平存在相关性（P〈0．05）。【结论】血浆Fetuin—A水平与AMI的发病风险相关。[ Objective ] To investigate the association of plasma Fetuin-A to acute myocardial infarction （AMI） amongst the Chinese Han nationality in Changwu District, Jiangsu. [ Methods] The ELISA method was used to detect plasma Fetuin-A in two groups with 86 cases of AMI patients （observation group） and 45 subjects without coronary artery disease （control group）. [ Results] The plasma Fetuin-A in AMI patients （426.14 ± 133.27g/L） was significantly higher than that in the control group （278.02 ±137.10g/L）. The difference was statistical significance （ P 〈 0.01 ）. After Logistic regression analysis with CAD （coronary artery disease） correction of risk factors （age, gender, cigarette, hypertension and diabetes）. Linear regression analysis showed that only age in the traditional risk factors for coronary heart disease had a relation to plasma Fetuin-A （ P 〈 0.05 ）. [ Conclusion ] Plasma Fetuin-A is related to AMI risks.

关 键 词：心肌梗死 急性病 甲胎蛋白类 危险因素 

分 类 号：R542.22[医药卫生—心血管疾病]