婴儿肝炎综合征患儿的血生化及肝脏病理变化与临床分析  

Clinical analysis of blood biochemical indexes and liver pathological changes in IHS

作　　者：范篆玲[1] 李立花 

机构地区：[1]宁夏医科大学,宁夏银川750001 [2]宁夏儿童福利院

出　　处：《中国民康医学》2016年第24期1-2,5,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:了解婴儿肝炎综合征(infantile hepatitis syndrome,IHS)患儿的血生化指标变化、肝脏的病理改变对其临床诊断及治疗预后的参考价值。方法:对10例婴儿肝炎综合征患儿的血生化指标采用全自动生化仪进行检测,肝脏穿刺进行的病理分析,并与临床症状、诊断进行对比分析。结果:婴儿肝炎综合征患儿的血生化指标异常变化明显,能较好的反映其肝受损的表现,肝脏的病理改变及其临床表现所示与婴儿肝综合征诊断符合率较高,大多数为胆汁淤积型为主,肝脏病理结果显示从肝细胞肿胀、点状坏死直至肝硬化均可见到,婴儿死亡率较高,治愈率低下。结论:血生化指标的检测及肝脏病理分析对婴儿肝炎综合征患儿的诊断、治疗及其预后分析有重要的参考价值。Objective：To understand changes of blood biochemical indexes and liver pathology in infantile hepatitis syndrome（IHS） in order to provide a reference value for its clinical diagnosis and treatment.Methods：The automatic biochemical analyzer was used to detect the blood biochemical indexes of 10 cases with IHS,and the pathological analysis was done through liver biopsy.Then,these results were compared with the clinical symptoms and diagnosis.Results：The abnormal changes of blood biochemical indexes in IHS were obvious,which could better reflect the performance of liver damage.As shown in the pathological changes and clinical manifestations of the IHS,the diagnosis mutual coincidence rate was higher,and the most was cholestasis type.Liver pathology results showed that swelling of liver cells,spotty necrosis of the liver and even liver cirrhosis all could be seen.Moreover,the child mortality rate was high,and the cure rate was low.Conclusions：The detection of blood biochemical indexes and liver pathological analysis has important reference values for the diagnosis,treatment and prognosis of IHS.

关 键 词：婴儿肝炎综合征 生化指标 肝病理变化 临床分析 

分 类 号：R725.126[医药卫生—儿科]