重症急性胰腺炎患者早期危险因素分析以及对预后的影响  

Analysis of early risk factors affecting the prognosis of patients with severe acute pancreatitis

作　　者：张露[1] 王玮[2] 

机构地区：[1]襄阳市中心医院湖北文理学院附属医院重症医学科,441021 [2]襄阳市中心医院湖北文理学院附属医院消化内科,441021

出　　处：《现代消化及介入诊疗》2016年第6期822-824,共3页Modern Interventional Diagnosis and Treatment in Gastroenterology

摘　　要：目的探讨重症急性胰腺炎(SAP)患者早期危险因素以及对预后的影响,为临床救治提供参考资料。方法选取64例SAP患者,根据患者的预后情况分为死亡组和生存组,分析其早期危险因素,其中单因素分析采用t检验,多因素分析采用Logistic回归分析。结果单因素分析结果显示,两组患者的年龄、BMI、通便时间、空腹血糖、血清白蛋白、血钙、动脉血氧分压、心率及呼吸频率差异具有统计学意义(P<0.05);Logistic回归分析结果显示,年龄、BMI、血清白蛋白、动脉血氧分压、心率、血钙差异具有统计学意义(P<0.05),其中危险因素为年龄、BMI、心率,保护因素为血清白蛋白、动脉血氧分压。结论年龄、BMI、心率均为SAP的危险因素,因此对于年龄大的、心率快的患者要重点监测,同时患者的血清白蛋白低、动脉血氧分压低时也要引起注意,可使用药物进行控制,提高患者的生存率。Objective To analyze the early risk factors affecting the prognosis of the patients withsevere acute pancreatitis in orderto provide the appropriate reference for clinical practice. Methods Sixty four patients with severe acute pancreatitis were divided into death group and survival group according to the prognosis. One single factor analysis was performed using student＇s t test, multivariate analysis using Logistic regression analysis. Results Univariate analysis showed that the factors including age, BMI, purge time, fasting blood glucose, serum albumin, calcium, blood pressure, heart rate, and respiratory rate were statistically significant difference （P 〈 0.05）. Logistic regression analysis showed that age, BMI, serum albumin, blood pressure, heart rate, blood calcium were into the equation and the difference was statistically significant （P 〈 0.05）. The risk factors were age, BMI and heart rate, the protection factors were serum albumin and arterial oxygen. Conclusion Age, BMI and heart rate are risk factors for severe acute pancreatitis. Therefore, the elderly patient with rapid heart rate should be focused on monitoring, while the patients with lower serum albumin and low arterial oxygenpressure should be paid more attention.

关 键 词：重症急性胰腺炎 早期危险因素 预后 

分 类 号：R725.4[医药卫生—儿科]