妈富隆治疗功能失调性子宫出血临床观察  

Clinical observation of marvelon in treating dysfunctional uterine bleeding

作　　者：赵中美 程鸽[1] 

机构地区：[1]山东省烟台市莱阳中心医院妇产科,265200

出　　处：《中国实用医药》2016年第35期120-122,共3页China Practical Medicine

摘　　要：目的探讨去氧孕烯炔雌醇片(商品名:妈富隆)治疗功能失调性子宫出血的临床治疗效果。方法 90例功能失调性子宫出血患者,随机分为治疗组和对照组,每组45例。治疗组采用口服妈富隆药物治疗,对照组采用临床传统药物(口服己烯雌酚)治疗。观察两组患者的治疗效果以及药物的不良反应。结果治疗组患者平均止血时间(3.5±1.3)d短于对照组(6.7±1.8)d,差异有统计学意义(P<0.05)。治疗后3个月治疗组止血后重建月经周期比例42.2%优于对照组13.3%,差异有统计学意义(P<0.05)。治疗组不良反应发生率13.33%低于对照组31.11%,差异有统计学意义(P<0.05)。结论妈富隆治疗功能失调性子宫出血的止血效果明显,可辅助重建月经周期,且药物不良反应少,治疗效果良好。Objective To explore the clinical effect of desogestrel and ethinylestradiol（trade name： marvelon） in treating dysfunctional uterine bleeding. Methods A total of 90 patients with dysfunctional uterine bleeding were randomly divided into treatment group and control group, with 45 cases in each group. The treatment group received oral marvelon for treatment, and control group received clinical conventional medicine（oral diethylstilbestrol） for treatment. Observation were made on clinical effect and adverse drug reactions. Results The treatment group had shorter mean hemostasis time as（3.5±1.3）d than（6.7±1.8）d in control group, and the difference had statistical significance（P〈0.05）.The treatment group had reconstruction of the menstrual cycle percentage after hemostasis in 3 months treatment as 42.2%, which was higher than 13.3% in control group, and the difference had statistical significance（P〈0.05）. The treatment group had lower adverse reaction rate as 13.33% than 31.11% in control group, and the difference had statistical significance（P〈0.05）. Conclusion Marvelon shows affirmative effect in treating dysfunctional uterine bleeding, for it can assist reconstruction of the menstrual cycle with little adverse drug reactions and excellent curative effect.

关 键 词：去氧孕烯炔雌醇片 功能失调性子宫出血 临床效果 

分 类 号：R711.52[医药卫生—妇产科学]