艾滋病合并急性盆腔炎患者临床抗生素治疗与观察  

Treatment and observation of clinical antibiotics to patients with AIDS combined with complicating acute pelvic inflammatory disease

作　　者：吴玉花[1] 邹才华[2] 李天资[2] 梁月秀[2] 黄秋艳[1] 李淑[1] 黄贞[1] 梁烨[2] 

机构地区：[1]广西壮族自治区百色市人民医院,广西百色533000 [2]右江民族医学院附属医院,广西百色533000

出　　处：《中国医药科学》2016年第19期9-12,共4页China Medicine And Pharmacy

基　　金：国家自然科学基金(81060028);广西壮族自治区重大专项基金(桂科重1598005-9;桂科攻15248001-7);广西壮族自治区百色市攻关基金(百科计20130402;20130403)

摘　　要：目的探讨艾滋病合并急性盆腔炎患者HIV合并感染型临床疗效的关联性,为规范本病治疗提供依据。方法对收治的艾滋病合并急性盆腔炎患者,分为HIV单独感染组(对照组)和HIV合并感染组(观察组)2组,对照组用HAART治疗3个月,观察组,在用抗生素治疗2周的基础上,联合用HAART治疗3个月,于治疗前后观察患者症状,体征,宫颈管分泌物镜检,CD4+T细胞计数和HIV病毒裁量变化。结果治疗后两组患者的腹胀、下腹部压痛、肌紧张,性交疼痛等症状消退;异常的阴道分泌物消退;子宫附件区压痛、宫颈举痛或摇摆痛体征消退;输卵管壁增厚、管腔积液、盆腔积液或输卵管卵巢脓肿等消退;阴道清洁度观察指标明显好转、CD4+T细胞计数提高数和HIV裁量降低数等指标组内比较有统计学意义(P<0.01),与对照比较无统计学意义(P>0.05)。结论对于艾滋病合并急性盆腔炎患者,临床上已经排除合并感染者,可单独用HAART治疗,发现有合并其他感染者,需要联合用抗生素治疗2周,可以很好地缓解患者的临床症状和体征,达到目的疗效。Objective To explore the relevance of clinical efficacy of HIV combined with infection to patients with AIDS combined with complicating acute pelvic inflammatory disease, to provide the basis for standardizing the treatment of this disease. Methods Patients with AIDS combined with complicating acute pelvic inflammatory disease cured in our hospital were divided into HIV single infected group（control group） and HIV combined infection group（observation group）. Patients in control group were treated with HAART for three months. Patients in observation group were treated with HAART for 3 months, On the basis of 2 weeks of treatment with antibiotics. Symptoms, signs, cervical tube secretions microscopy, CD4＋T cell count and changes of HIV virus discretion before and after the treatment were observed. Results Abdominal distension, abdominal tenderness, muscle tension, sexual intercourse pain and other symptoms of the two groups after treatment were disappeared. Abnormal vaginal discharge was disappeared. Tenderness of uterine accessory area, palace neck lift is painful or shake painful sign were disappeared. Tubal wall thickening, lumen effusion, pelvic effusion or fallopian tube ovarian abscess, etc. were disappeared. Vaginal cleanliness was improved significantly. There was statistical significance on CD4^＋T cell increased count, HIV cut down number and other indicates in the group（P〈0.01）. There was no statistical significance compared with the control group（P 〉0.05）. Conclusion For AIDS patients with acute pelvic inflammatory disease, merge infection has been ruled out clinically. It can be separately treated with HAART. If there was a combination of other infections, 2 weeks of treatment with antibiotics were needed. It can well relieve the patient＇s clinical symptoms and signs, to achieve the purpose of efficacy.

关 键 词：艾滋病 急性盆腔炎 合并感染 抗病毒治疗 

分 类 号：R512.91[医药卫生—内科学]