山东省交通医院门诊抗菌药物超说明书用药情况调查  

Off -label use of antibacterial agents in Traffic Hospital of Shandong Province in 2016：a cross sectional study

作　　者：管玉瑶 任少玉 任继波 王军成[1] 齐本彬 宋超[1] Guan Yuyao Ren Shaoyu Ren Jibo Wang Juncheng Qi Benbin Song Chao(Department of Pharmacy, Shandong Provincial Traffic Hospital, Ji ＇ nan , Shandong 250031, China Drug Research and Development Center of SDU ＆ Shandoag Qidu Pharmaceutical Co,Ltd. Ji＇nan, Shandong 250001, China)

机构地区：[1]山东省交通医院药学部,山东省济南250031 [2]山东齐都药业有限公司山大齐都药物研发中心,山东省济南250001

出　　处：《中国基层医药》2017年第1期27-30,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：中国药学会科技开发中心委托研究项目（2012DCST04EM03）

摘　　要：目的：了解山东省交通医院门诊抗菌药物超说明书用药情况，对其用药现状进行调查与分析。方法随机抽取山东省交通医院2016年1～4月门诊抗菌药物处方，根据药品说明书判断是否属于超说明书用药。结果共抽取门诊抗菌药物处方1264张，其中涉及抗菌药物58种。超说明书用药主要包括超适应人群（23．42％）、适应证（4．15％）、剂量（6．31％）、给药频次（62．95％）、给药途径（3．15％）。结论门诊抗菌药物超说明书用药现象较为普遍，应对超说明书用药进行规范管理。Objective To determine the off -label use of antibacterial agents,we investigated and analyzed the current status about off -label use of antibacterial agents.Methods The random sampling was conducted to select the outpatient prescription including antibacterial agents from January to April in 2016.According to drug instructions,the off -label drug use of prescription was analyzed.Results 1 264 prescriptions involving 58 kinds of drugs were analyzed.The main categories of off -label drug use were no pediatric and elderly information（23.42%）, indication（4.1 5%）,dosage （6.31 %）,dosage range （62.95%）and administration route （3.1 5%）.Conclusion The off -label use of antibacterial agents is common in our hospital.It＇s in need to regulate off -label drug use.

关 键 词：说明书 药物处方 抗菌药 门诊医疗 

分 类 号：R95[医药卫生—药学]