Transfer of convalescent serum to pregnant mice prevents Zika virus infection and microcephaly in offspring  

作　　者：Shuo Wang Shuai Hong Yong-Qiang Deng Qing Ye Ling-Zhai Zhao Fu-Chun Zhang Cheng-Feng Qin Zhiheng Xu 

机构地区：[1]State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China [2]University of Chinese Academy of Sciences, Beijing 100101, China [3]Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China [4]Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China [5]Parkinson's Disease Center, Beo'ing Institute for Brain Disorders, Beijing 100101, China

出　　处：《Cell Research》2017年第1期158-160,共3页细胞研究（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China （31430037, 31271156, 81522025 and 81621005）, the National Basic Research Program （＂973＂ program;2014CB942801, 2013DFA31990 and 2012YQ03026006） and the National Key Research Program of China （2016YFD0500304）.

摘　　要：Zika virus （ZIKV） is spreading rapidly around the world in over 60 countries. There is a mounting concern over the association of ZIKV infection and devastating cases of fetal and newborn microcephaly cases [1]. The connection between ZIKV infection and microcephaly was first proposed based on the presence of ZIKV in microcephalic fetal brain tissues .

关 键 词：病毒感染 畸形 恢复期 后代 老鼠 怀孕 血清 胎脑组织 

分 类 号：S858.28[农业科学—临床兽医学] S831.2[农业科学—兽医学]