RT-3DE技术评估早期慢性肾病患者左心室收缩同步性  

Assessment of Left Ventricular Systolic Synchronicity in Patients with Early Chronic Kidney Disease by RT-3DE

作　　者：许立岩 张新书[1] 姜凡[1] 解翔[1] 卢业伟[1] 方思华[1] 伍婷婷[1] 

机构地区：[1]安徽医科大学第二附属医院超声诊断科,合肥市230601

出　　处：《中国超声医学杂志》2017年第2期125-128,共4页Chinese Journal of Ultrasound in Medicine

基　　金：安徽医科大学校临床科学研究项目(No.2015xkj110)

摘　　要：目的通过实时三维超声心动图(RT-3DE)评估早期慢性肾脏病(CKD)患者左心室收缩同步性。方法根据肾小球滤过率(GRF)将40例慢性肾脏病患者分为两组,分别为CKD1-2期组20例和CKD3-5期组20例,另随机选取20例体检正常人群作为对照组,先分别对3组行常规超声心动图一般参数的测量,然后再运用RT-3DE技术对每组左室收缩同步性的相应参数和时间-曲线变化进行分析评估。结果 (1)常规超声心动图:与对照组相比,CKD1-2期组舒张末期室间隔厚度(IVSTd)增加,差异有统计学意义(P<0.05),左室后壁厚度(LVPWd)比较差异无统计学意义(P>0.05)。CKD3-5期组IVSTd、LVPWd明显高于对照组(P<0.01);三组间的左室射血分数的差异无统计学意义(P>0.05)。(2)RT-3DE:CKD1-2期17节段容积-时间曲线较正常组有变化,走形高低不一,部分测量参数(Tmsv-6SD/R-R、Tmsv-16Dif/R-R、Tmsv-6Dif/R-R)较正常对照组增高,差异有统计学意义(P<0.05);CKD 3-5期组曲线变化更为显著且大部分参数均明显高于对照组(P<0.01)。结论 CKD早期患者的左室收缩同步性已发生改变,可通过RT-3DE技术进行评估。Objective To assess left ventricular systolic synchronicity in patients with early chronic kidney dis ease by real-time three-dimensional echocardiography（RT-3DE）. Methods A total of 40 patients with chronic kidney disease were divided into CKD1-2 group （n= 20） and CKD3- 5 group （n= 20） according to the glomerular filtration rate （GRF）,and 20 control subjects were enrolled in this study. All subjects underwent routine eehocardiography and RT-3DE,and then were analyzed using QLAB software to obtain 17-segmental volume-time curves and the data of left ventricular systolic synchronicity. Results （1）Conventional echoeardiography： Compared with normal control group, the IVSTd at end diastole in CKD1-2 group were increased, and there had significant difference （P〈0.05）, but there were no significant difference of LVPWd（P〉0.05）. The IVSTd and LVPWd of CKD3-5 group were obviously higher than that of normal control group （P〈0.01）. There was no significant difference of LVEF among three groups（P〉 0.05）. 2）RT-3DE：Compared with normal group, the 17-segmental volume-time curves of CKD1- 2 group changed and parts of the data（Tmsv-6SD/R-R,Tmsv-16Dif/R-R.Tmsv 6Dif/R-R） of left ventricular systolic synchronicity increased, and there had significant difference （P%0.05）. The change of the 17-segmental volume-time curves of CKD3 -5 group were more obvious and most of the parameters were significantly higher than that of normal control group （P〈0.01）. Conclusions The left ventricular systolic synchronicity in patients with early chronic kidney disease has been changed and can be estimated by RT-3DE.

关 键 词：超声心动图 三维 慢性肾脏病 早期 左室收缩同步性 

分 类 号：R540.45[医药卫生—心血管疾病] R692[医药卫生—内科学]