中药麦冬本草溯源释疑  

Textual Research of Chinese Herb Maidong

作　　者：龚亚君[1] 张洁[1] 项志南 周成高 陈家春[1] Gong Yajun Zhang Jie Xiang Zhinan Zhou Chenggao Chen Jiachun(Hubei Key Laboratory of Natural Medicinal Chemistry and Re- source Evaluation, Tongji School of Pharmaceutical Sciences, Huazhong University of Science and Technology, Wuhan 430030, Chin)

机构地区：[1]华中科技大学同济医学院药学院天然药物化学与资源评价湖北省重点实验室,武汉430030

出　　处：《中国药师》2017年第2期229-231,共3页China Pharmacist

基　　金：国家自然科学基金(编号:30873373;81373917);国家"重大新药创制"科技重大专项(编号:2011ZX09102-004-02)

摘　　要：目的:通过对麦冬的名称、基原、产地等进行本草考证,明确麦冬入药的历史沿革,澄清麦冬入药品种,为临床用药提供依据。方法:考证历代本草著作,结合资源调查及现代资料进行分析。结果:从历代本草记述来看,麦门冬的别名虽多,但并未流传成常用名。药材名只有"麦门冬"和"麦冬"。根据本草记载的麦门冬主要产地、原植物的形态特征和药用情况,可以初步推断历代本草记载的麦冬主要产于我国浙江建德,四川绵阳,湖北襄阳及周边地区。麦冬与山麦冬化学成分、药理作用基本类似。在中医临床上倾向于等同入药。结论:鉴于古今麦冬药用习惯、现代化学与药理研究基础和中医临床实际,麦冬和山麦冬能否参照寥科植物掌叶大黄palmatum L.、唐古特大黄Rheum tanguticum Maxim,ex Balf.或药用大黄Rheum officinale Baill.;毛茛科植物黄连Coptis chinensis Franch.、三角叶黄连Coptis deltoidea C.Y.Cheng et Hsiao或云连Coptisteeta Wall.等常用中药,作为中药多来源品种对待可进一步磋商讨论。Objective： To perform textual researches on name, origin and distribution of Maidong to clarify the medicinal varieties and history recorded in ancient literatures and provide evidence for clinical use. Methods： Ancient herbal works were performed textual research, and the resource investigation and modem data were analyzed. Results： According to the ancient herbal records and modem researches, Maidong had lots of alias, while only Maimendong and Maidong were used as the medicine common names. According to the records of main origin, original plant morphological and medicinal characteristics of Maimendong, it was preliminarily concluded that Maidong recorded in the ancient herbal records was mainly produced in Jiande of Zhejiang province, Mianyang of Sichuan prov- ince, Xiangyang of Hubei province and the surrounding areas. The chemical compositions and pharmacological activities of Maidong and Shanmaidong were similar; therefore, they both could be used as the medicines. Conclusion： In the light of the ancient and mod- em medicinal customs, modem chemistry and pharmacology researches and clinical practice of TCM, it deserves further discussion on whether Maidong and Shanmaldong can be used as multi source varieties of traditional Chinese medicines just like Polygonaceae plants palmatum L. , Rheum tanguticum Maxim, ex Balf. and Rheum officinale Baill. , and Ranunculaceae plants Coptis chinensis Franch. , Coptis deltoidea C. Y. Cheng et Hsiao and Coptisteeta Wall.

关 键 词：麦冬 湖北麦冬 本草考证 

分 类 号：R282.71[医药卫生—中药学]